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Imaging of Latent Fingerprints through the Detection of Drugs and Metabolites

Imaging of Latent Fingerprints through the Detection of Drugs and Metabolites. Pompi Hazarika, Sue M. Jickells, Kim Wolff, and David A. Russell*. Angew. Chem. Int. Ed. 2008 , 47 , 10167 –10170. Antibody–magnetic-particle.

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Imaging of Latent Fingerprints through the Detection of Drugs and Metabolites

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  1. Imaging of Latent Fingerprints through the Detection of Drugs and Metabolites Pompi Hazarika, Sue M. Jickells, Kim Wolff, and David A. Russell* Angew. Chem. Int. Ed. 2008, 47, 10167 –10170

  2. Antibody–magnetic-particle • These conjugates are attractive as not only can they provide evidence of drug use but they also enable identification of an individual with the ease of application and removal of magnetic fingerprint powder.

  3. Detection of drugs

  4. Detection of THC in a fingerprint

  5. Detection of THC in a fingerprint

  6. Detection of methadone and EDDP in a fingerprint

  7. Detection of methadone in a fingerprint

  8. Detection of EDDP in a fingerprint

  9. Detection of benzoylecgonine in a fingerprint

  10. Detection of benzoylecgonine in a fingerprint

  11. Conclusions • It has been shown for the first time that various drugs and drug metabolites, such as THC, methadone and its metabolite EDDP, and benzoylecgonine can be readily detected in latent fingerprints of drug users through the use of antibody–magnetic-particle conjugates imaged by using either brightfield and/or fluorescence microscopy. • The fluorescence imaging capability of latent fingerprints provides a method that is potentially more sensitive for trace residue detection. • A key advantage of the magnetic-particle conjugates is that excess reagents can be removed using a magnet in a process similar to that currently used by fingerprint examiners at the scene of a crime.

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