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No. 170. Analysis of t ransperineal b iopsy and subsequent r adical p rostatectomy SA-PCCOC database ). Osei - Tutu L , Lee J Repatriation General Hospital, South Australia. Posters Proudly Supported by:. Results

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Introduction

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  1. No. 170 Analysis of transperinealbiopsy and subsequent radical prostatectomySA-PCCOC database) Osei- Tutu L , Lee J Repatriation General Hospital, South Australia. Posters Proudly Supported by: • Results • A total of 51 patients had a TP biopsy, out of 4492 patients recruited to the SA-PCCOC database in this time period. Of these, 23 patients subsequently had a radical prostatectomy. • Mean age was 64.6 years (range 53.4-73.1 years). • The indications for TP biopsy were: • Following negative standard TRUS biopsy: 13 patients (56.5%) • Following positive standard TRUS biopsy: 8 patients (34.8%) • Primary biopsy performed: 2 patients (8.7%) • Ten (43.5%) of patients were upgraded, with seven (30.4%) downgraded and 6 (26.1%) maintained the original grade of their malignancy. Introduction Accurate grading of prostate cancer affects treatment decision s in patients with Gleason 6 or 7 prostate cancer. In Gleason 3+4 prostate cancer, upgrading on subsequent radical prostatectomy (RP) can occur in up to 27% of patients. Aim The South Australia Prostate Cancer Clinical Outcomes Collaborative (SA-PCCOC )database captures approximately 50% of all new prostate cancer diagnosis in South Australia. This is a clinical audit to examine patients who had a transperineal (TP) biopsy and a subsequent RP to assess the rate of upgrading of TP biopsy in a population based setting. Methods All patients who had a TP biopsy in the SA-PCCOC dataset who had a subsequent RP were identified. The time period was May 2007 (first recorded TP biopsy on the database) – July 2012. Data regarding PSA results and histology for any standard TRUS biopsies, TP biopsies and radical prostatectomy was extracted. Ethics approval: Southern Adelaide Clinical Human Research Ethics Committee, Number: 202.12. Conclusions A significant proportion of TP biopsy patients were upgraded on RP. TP biopsy is not an accurate means of grading prostate cancer. Captions to be set in Arial font italic and RP weight / Number of Cores References Accuracy of primary systematic template guided transperineal biopsy of the prostate for locating prostate cancer: a comparison with radical prostatectomy specimens. Huo AS, Hossack T, Symons JL, PeBenito R, Delprado WJ, Brenner P, Stricker PD. J Urol. 2012 Jun;187(6):2044-9. doi: 10.1016/j.juro.2012.01.066. Epub 2012 Apr 11. Acknowledgements SA-PCCOC database staff - Carole Pinnock, Tina Kopsaftis, Scott Walsh

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