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Annual Report on Intestine Transplantation 2022/23 Slide Set

The annual report on intestine transplantation for 2022/23 provides detailed insights into the number of patients on the active intestine transplant list, registrations, outcomes, and total transplants in the UK. The report includes data on patients on the active list by center, registrations onto the list, post-registration outcomes, and total number of intestine transplants from April 2012 to March 2023.

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Annual Report on Intestine Transplantation 2022/23 Slide Set

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  1. Annual Report on Intestine Transplantation 2022/23 SLIDE SET Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant

  2. Introduction

  3. Figure 2.1 Patients on the active intestine transplant list at 31 March Figure 2.1 Patients on the active intestine transplant list at 31 March 20 20 19 19 18 18 16 16 14 13 14 14 14 14 14 13 12 12 12 12 11 11 Number Number 10 10 10 9 9 8 8 6 6 6 6 6 6 4 4 2 2 0 0 2013 2014 2014 2015 2015 2016 2016 2017 2017 2018 2018 2019 2019 2020¹ 2020¹ 2021 2022 2022 2023 Year Year ¹ Waiting list as at 29 February 2020 ¹ Waiting list as at 29 February 2020 Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  4. Figure 2.2 Patients on the active intestine transplant list at 31 March 2022, by centre Figure 2.2 Patients on the active intestine transplant list at 31 March 2023, by centre 10 10 Paediatric Paediatric Adult Adult 9 9 9 8 8 7 7 6 6 Number Number 5 5 5 4 4 3 3 2 2 2 2 2 2 1 1 1 1 0 0 Birmingham Birmingham Cambridge Cambridge King's College King's College Oxford Oxford Transplant Centre Transplant Centre Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  5. Figure 2.3 Number of registrations onto the active intestine transplant list, 1 April 2012 - 31 March 2022 Figure 2.3 Number of registrations onto the active intestine transplant list, 1 April 2013 - 31 March 2023 40 40 34 34 32 32 31 31 29 30 30 28 28 27 27 27 27 No. of registrations No. of registrations 23 23 20 20 20 20 18 16 16 10 10 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2014/2015 2015/2016 2015/2016 2016/2017 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2019/2020 2020/2021 2020/2021 2021/2022 2021/2022 2022/2023 Financial Year Financial Year Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  6. Figure 2.4 Registrations onto the active intestine transplant list, 1 April 2021 - 31 March 2022, by centre Figure 2.4 Registrations onto the active intestine transplant list, 1 April 2022 - 31 March 2023, by centre 25 25 Paediatric Paediatric Adult Adult 20 20 19 16 15 15 Number Number 10 10 8 6 5 5 5 5 2 2 0 0 Birmingham Birmingham Cambridge Cambridge King's College King's College Oxford Oxford Transplant Centre Transplant Centre Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  7. Figure 2.5 Post-registration outcome for 52 elective registrations for an intestine transplant Figure 2.5 Post-registration outcome for 59 elective registrations for an intestine transplant made in the UK, 1 April 2018 - 31 March 2020 made in the UK, 1 April 2019 - 31 March 2021 100 100 8 10 8 10 12 13 90 90 8 8 10 12 10 12 80 80 15 13 70 70 24 19 37 42 Percentage Percentage 60 60 50 50 40 40 63 62 30 30 58 60 46 40 20 20 10 10 0 0 6 months 6 months 1 year 1 year 2 years 2 years Time since listing Time since listing Transplanted Transplanted Still waiting Still waiting Removed Removed Died Died Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  8. Figure 2.6 Total number of intestine transplants, 1 April 2012 - 31 March 2022 Figure 2.6 Total number of intestine transplants, 1 April 2013 - 31 March 2023 30 30 27 27 26 26 26 26 25 24 24 20 20 20 20 No. of transplants No. of transplants 19 19 15 15 15 15 14 12 12 10 10 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2014/2015 2015/2016 2015/2016 2016/2017 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2019/2020 2020/2021 2020/2021 2021/2022 2021/2022 2022/2023 Financial Year Financial Year Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  9. Figure 2.7 UK intestine transplants, 1 April 2013 to 31 March 2023 All transplants involving intestine 1 April 2013 – 31 March 2023 2091 Paediatric 50 Adult 159 Re-transplants 8** First intestine transplants 151* Re-transplants 7 First intestine transplants 432 1Excludes one abdominal wall only transplant (October 2016) 2 Includes one living donor liver and bowel transplant (June 2017) * Five of these transplants were super-urgent ** Two of these transplants were super-urgent Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  10. Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  11. Adult Activity

  12. Figure 3.1 Adult patients on the intestine transplant list at 31 March, 2013 - 2022 Figure 3.1 Adult patients on the intestine transplant list at 31 March, 2014 - 2023 20 20 18 18 15 15 15 15 15 13 Number Number 11 11 10 10 10 10 10 10 10 9 10 10 9 9 8 7 8 8 8 8 8 8 7 8 7 7 7 7 5 5 5 5 5 5 5 5 5 5 5 5 5 5 6 5 5 4 4 3 3 3 4 4 2 2 2 2 2 2 0 0 2013 2014 2014 2015¹ 2015¹ 2016 2016 2017 2017 2018 2018 2019 2019 2020² 2020² 2021 2021 2022 2022 2023 Year Year Active Active Suspended Suspended Total Total ¹ Excludes one patient at Oxford registered for abdominal wall only ¹ Excludes one patient at Oxford registered for abdominal wall only ² Waiting list as at 29 February 2020 ² Waiting list as at 29 February 2020 Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  13. Figure 3.2 Adult patients on the intestine transplant list at 31 March, by centre, 2013 - 2022 Figure 3.2 Adult patients on the intestine transplant list at 31 March, by centre, 2014 - 2023 Cambridge Cambridge Oxford Oxford 15 15 10 10 Number Number 5 5 0 0 2013 2014 2014 2015 2015 2016 2016 2017 2017 2018 2018 2019 2020² 2021 2019 2020² 2021 2022 2022 2023 2013 2014 2015¹ 2016 2014 2015¹ 2016 2017 2017 2018 2018 2019 2020² 2021 2019 2020² 2021 2022 2022 2023 Year Year Active Active Suspended Suspended Total Total ¹ Excludes one patient at Oxford registered for abdominal wall only ¹ Excludes one patient at Oxford registered for abdominal wall only ² Waiting list as at 29 February 2020 ² Waiting list as at 29 February 2020 Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  14. Figure 5.1 Adult intestine transplants in the UK, 1 April 2012 - 31 March 2022 Figure 5.1 Adult intestine transplants in the UK, 1 April 2013 - 31 March 2023 30 30 Non liver containing Non liver containing Liver containing Liver containing 25 25 23 23 21 20 20 No. of transplants No. of transplants 20 20 18 18 17 17 16 16 15 15 15 15 12 12 11 11 10 10 10 6 6 5 5 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2014/2015 2015/2016 2015/2016 2016/2017 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2019/2020 2020/2021 2020/2021 2021/2022 2021/2022 2022/2023 Financial Year Financial Year Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  15. Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  16. Figure 5.3 Adult intestine transplants by centre, 1 April 2012 - 31 March 2022 Figure 5.3 Adult intestine transplants by centre, 1 April 2013 - 31 March 2023 Cambridge Cambridge Oxford Oxford 20 20 18 16 16 15 15 14 14 14 14 No. of transplants No. of transplants 12 12 11 11 10 10 9 9 8 8 8 8 7 7 6 6 6 6 6 6 5 5 5 5 4 5 5 5 5 4 4 3 4 3 3 0 0 0 0 2013/2014 2012/2013 2013/2014 2014/2015 2014/2015 2015/2016 2015/2016 2016/2017 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2020/2021 2019/2020 2021/2022 2020/2021 2022/2023 2021/2022 2013/2014 2012/2013 2013/2014 2014/2015 2014/2015 2015/2016 2016/2017 2015/2016 2017/2018 2016/2017 2018/2019 2017/2018 2019/2020 2018/2019 2020/2021 2019/2020 2021/2022 2020/2021 2021/2022 2022/2023 Financial year Financial year Non liver containing Non liver containing Liver containing Liver containing Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  17. Figure 5.4 Median cold ischaemia time in adult intestine transplants, Figure 5.4 Median cold ischaemia time in adult intestine transplants, 1 April 2012 - 31 March 2022 1 April 2013 - 31 March 2023 10 10 9 9 Cold ischaemia time (hours) Cold ischaemia time (hours) 8 8 7 7 6 6 5 5 4 4 3 3 2 2 1 1 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2014/2015 2015/2016 2015/2016 2016/2017 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2019/2020 2020/2021 2020/2021 2021/2022 2021/2022 2022/2023 Year Year Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  18. Figure 5.5 Median cold ischaemia time in all adult intestine transplants, Figure 5.5 Median cold ischaemia time in all adult intestine transplants, 1 April 2012 - 31 March 2022 1 April 2013 - 31 March 2023 Cambridge Cambridge Oxford Oxford 10 10 9 9 Cold ischaemia time (hours) Cold ischaemia time (hours) 8 8 7 7 6 6 5 5 4 4 3 3 2 2 1 1 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2015/2016 2014/2015 2015/2016 2016/2017 2017/2018 2016/2017 2017/2018 2018/2019 2018/2019 2019/2020 2020/2021 2019/2020 2020/2021 2021/2022 2022/2023 2021/2022 2013/2014 2012/2013 2014/2015 2013/2014 2015/2016 2014/2015 2015/2016 2016/2017 2017/2018 2016/2017 2018/2019 2017/2018 2019/2020 2018/2019 2020/2021 2019/2020 2020/2021 2021/2022 2021/2022 2022/2023 Year Year Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  19. Paediatric Activity

  20. Figure 7.1 Paediatric patients on the intestine transplant list at 31 March, 2013 - 2022 Figure 7.1 Paediatric patients on the intestine transplant list at 31 March, 2014 - 2023 15 15 14 14 13 13 12 12 11 11 11 11 10 10 10 10 10 10 10 10 9 9 Number Number 8 8 8 8 8 8 7 7 7 7 7 7 7 7 6 6 6 6 6 5 5 5 5 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 2 3 3 2 2 2 2 1 1 1 1 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2013 2014 2014 2015 2015 2016 2016 2017 2017 2018 2018 2019 2019 2020¹ 2020¹ 2021 2021 2022 2022 2023 Year Year Active Active Suspended Suspended Total Total ¹ Waiting list as at 29 February 2020 ¹ Waiting list as at 29 February 2020 Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  21. Figure 7.2 Paediatric patients on the intestine transplant list at 31 March, by centre, 2013 - 2022 Figure 7.2 Paediatric patients on the intestine transplant list at 31 March, by centre, 2014 - 2023 Birmingham Birmingham King's College King's College 10 10 9 9 8 8 7 7 6 6 Number Number 5 5 4 4 3 3 2 2 1 1 0 0 2013 2014 2014 2015 2015 2016 2016 2017 2017 2018 2018 2019 2020¹ 2021 2019 2020¹ 2021 2022 2022 2023 2013 2014 2014 2015 2015 2016 2016 2017 2017 2018 2018 2019 2020¹ 2021 2019 2020¹ 2021 2022 2022 2023 Year Year Active Active Suspended Suspended Total Total ¹ Waiting list as at 29 February 2020 ¹ Waiting list as at 29 February 2020 Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  22. Figure 9.1 Paediatric intestine transplants in the UK, 1 April 2012 - 31 March 2022 Figure 9.1 Paediatric intestine transplants in the UK, 1 April 2013 - 31 March 2023 15 15 Non liver containing Non liver containing Liver containing Liver containing No. of transplants No. of transplants 10 10 9 9 8 8 7 7 6 6 5 5 4 4 4 4 3 3 3 3 3 3 3 3 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2014/2015 2015/2016 2015/2016 2016/2017 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2019/2020 2020/2021 2020/2021 2021/2022 2021/2022 2022/2023 Financial Year Financial Year Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  23. Figure 9.2 Paediatric intestine transplants in the UK by centre, 1 April 2021 - 31 March 2022 Figure 9.2 Paediatric intestine transplants in the UK by centre, 1 April 2022 - 31 March 2023 Non liver containing Non liver containing Liver containing Liver containing 6 6 5 5 4 No. of transplants No. of transplants 4 4 3 3 3 2 2 2 2 1 1 0 0 Birmingham Birmingham King's College King's College Transplant centre Transplant centre Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  24. Figure 9.3 Paediatric intestine transplants by centre, 1 April 2012 - 31 March 2022 Birmingham 15 15 Figure 9.3 Paediatric intestine transplants by centre, 1 April 2013 - 31 March 2023 Birmingham King's College King's College No. of transplants No. of transplants 10 10 5 5 4 5 5 5 5 4 4 4 4 4 4 4 3 3 3 3 3 3 3 3 2 2 2 2 1 2 2 2 2 1 1 1 0 1 1 1 1 0 0 0 0 0 2013/2014 2012/2013 2014/2015 2013/2014 2014/2015 2015/2016 2016/2017 2015/2016 2016/2017 2017/2018 2018/2019 2017/2018 2019/2020 2018/2019 2020/2021 2019/2020 2020/2021 2021/2022 2022/2023 2021/2022 2012/2013 2013/2014 2014/2015 2013/2014 2014/2015 2015/2016 2016/2017 2015/2016 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2020/2021 2019/2020 2020/2021 2021/2022 2022/2023 2021/2022 Financial year Financial year Non liver containing Non liver containing Liver containing Liver containing Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Transplants may also include any of stomach, spleen, abdominal wall, kidney, colon. Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  25. Figure 9.4 Median cold ischaemia time in paediatric intestine transplants, Figure 9.4 Median cold ischaemia time in paediatric intestine transplants, 1 April 2012 - 31 March 2022 1 April 2013 - 31 March 2023 14 14 12 12 Cold ischaemia time (hours) Cold ischaemia time (hours) 10 10 8 8 6 6 4 4 2 2 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2014/2015 2015/2016 2015/2016 2016/2017 2016/2017 2017/2018 2017/2018 2018/2019 2018/2019 2019/2020 2019/2020 2020/2021 2020/2021 2021/2022 2021/2022 2022/2023 Year Year Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

  26. Figure 9.5 Median cold ischaemia time in all paediatric intestine transplants, Figure 9.5 Median cold ischaemia time in all paediatric intestine transplants, 1 April 2012 - 31 March 2022 1 April 2013 - 31 March 2023 Birmingham Birmingham King's College King's College 14 14 12 12 Cold ischaemia time (hours) Cold ischaemia time (hours) 10 10 8 8 6 6 4 4 2 2 0 0 2012/2013 2013/2014 2013/2014 2014/2015 2015/2016 2014/2015 2016/2017 2015/2016 2016/2017 2017/2018 2017/2018 2018/2019 2019/2020 2018/2019 2020/2021 2019/2020 2021/2022 2020/2021 2021/2022 2022/2023 2013/2014 2012/2013 2014/2015 2013/2014 2015/2016 2014/2015 2015/2016 2016/2017 2017/2018 2016/2017 2018/2019 2017/2018 2019/2020 2018/2019 2019/2020 2020/2021 2020/2021 2021/2022 2021/2022 2022/2023 Year Year Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Cardiothoracic Organ Transplantation 2021/2022, NHS Blood and Transplant Source: Annual Report on Intestine Transplantation 2022/23, NHS Blood and Transplant

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