BIO 430: Forensic DNA Analysis - PowerPoint PPT Presentation

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BIO 430: Forensic DNA Analysis

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    1. BIO 430: Forensic DNA Analysis Lecture 2 History of DNA typing

    3. History of DNA Typing 1986 - RFLP first used in Forensic setting in England to solve a double homicide case 1988 - FBI starts DNA casework 1990 Human Genome project initiated 1991 Fluorescent STR markers first described

    4. History of DNA Typing 1992 FBI starts casework using PCR-based techniques 1993 First STR kits become available 1994 O.J. Simpson trial; first publicized case involving DNA evidence

    5. History of DNA Typing 1995 - FSS (Forensic Science Service-UK) starts UK DNA database 1996 First multiplex STR kits become available 1998 - FBI launches CODIS (Combined DNA Information Service); now FBI use 13 STR loci

    6. History of DNA Typing 2000 FBI and other labs stop running RFLP cases and convert to multiplex STRs 2003 Human Genome Project completed (mostly)

    7. Sources of Biological Evidence Blood Semen Saliva Urine Hair Teeth Bone Tissue

    8. Steps in DNA Sample Processing