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Integration of TB and HIV Services A Case Study of Kericho District Hospital. Hellen Muttai, MBChB, MPH Clinical Care Manager South Rift Valley HIV Care & Treatment Program Kenya Medical Research Institute/Walter Reed Project. Why Integration?. TB Clinic. HIV Clinic. Patients

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integration of tb and hiv services a case study of kericho district hospital

Integration of TB and HIV Services A Case Study of Kericho District Hospital

Hellen Muttai, MBChB, MPH

Clinical Care Manager

South Rift Valley HIV Care & Treatment Program

Kenya Medical Research Institute/Walter Reed Project

slide2

Why Integration?

TB Clinic

HIV

Clinic

Patients

Patient’s hospital time

Double clinics, queues, drug prescriptions, sets of labs, different clinic days

Programmatic

Low uptake of collaborative services

Clinicians

Focusing on individual diseases in one patient

slide3

Integrated TB/HIV clinic opened July 2005

HIV Clinic

In-patient

Out-patient

Integrated TB/HIV Clinic

TB Diagnosis and Treatment (for both HIV negative patients

HIV Testing & Counseling (for all TB patients)

HIV Surveillance

TB and HIV Care & Treatment (for co-infected patients)

Co-trimoxazole Preventive Therapy

HIV Prevention

TB Treatment Completion

methods
Methods
  • Retrospective TB/HIV Clinic chart review
    • All patients seen in the clinic during a 18 month period
    • Advantage of electronic medical records system
achievements
Achievements
  • Provider Initiated Testing and Counseling (PITC)
    • Total TB pts seen in 2006:1226
    • Tested for HIV- 1155: Testing rate 94.2%
    • National PITC Uptake- 60% (2006)
  • Routine HIV surveillance among TB patients
    • HIV+ 525: Co-infection rate 45.4%
  • Routine HIV prevention services among TB and TB/HIV co-infected patients
  • Co-trimoxazole preventive therapy
    • 100% uptake
    • National Uptake- 87% (2006)
slide6
Uptake of HIV Care and Treatment

100% of co-infected patients offered HIV Care and Treatment services

Eligible for ART- 78%

100% (of eligible) started on ART

(56.1% started in course of TB treatment; 22% started after completion of TB treatment)

National ART Uptake-26% (2006)

Clinicians tying the management of both diseases together

Reduction in time spent in hospital by patients

Achievements

tb hiv clinic summary
TB/HIV Clinic Summary

Patients Enrolled = 792 (July 2005 to Dec. 2006)

Characteristic No. %

Female 435 55%

Age (yrs, mean/SD) 33.1 (+12.3)

TB Characteristics

Pulmonary 697 89%

Smears done (PTB) 626 90%

smear – (smears done) 377 60%

Baseline CD4 (cells/mm3)

<100 266 36.9%

100-199 166 23.1%

200-349 144 18.0%

>350 157 22.0%

treatment outcomes for co infected patients
Treatment Outcomes for Co-infected Patients

Mean 6-Month CD4 Change (cells/mm3)

Care +78*

ART +139*

TB Treatment Outcome

No. %

Completed 507 64%

Transferred out 87 11%

Loss to Follow up 111 14%

Deaths 87 11%

Total 792 100%

p value <0.001

strengths conclusions
Strengths/ Conclusions
  • PROGRAM/ CLINIC LEVEL
    • Successful management of co-infected patients with good clinical outcomes
    • Successful integration of TB and HIV services at a district hospital setting
    • High uptake of TB/HIV collaborative services
  • ANALYTIC
    • Patients with combined TB/HIV infections may receive benefit from:
      • primary TB treatment (“care”) alone
      • and additionally ART
    • Patients with combined TB/HIV infections often present with advanced HIV disease
limitations
Limitations
  • PRIMARY:
    • Inherent limitations in retrospective chart reviews
      • Clinic set-up not designed for systematic research
      • Incomplete/missing clinical data
recommendations
Recommendations
  • Integration of TB and HIV services needs to be considered in health facilities in order to improve uptake of collaborative services
  • Clinicians treating patients with TB/HIV should be aware of the benefit to HIV infection by treating TB and offering supportive care alone, and additionally ART.
  • Efforts to identify patients with TB/HIV early in their disease may offer tangible benefit by providing the opportunity to consider early ART.
  • Further controlled studies are needed to best identify when (and what settings) to initiate ART in patients receiving TB treatment.
slide12

Acknowledgements

  • Kericho District Hospital TB/HIV Clinic
  • Kenya Ministry of Health/NLTP/NASCOP
  • President’s Emergency Plan for AIDS Relief
  • Kericho District Hospital - Eunice Obiero
  • KEMRI – Fredrick Sawe & Charles Sigei
  • USMHRP – Douglas Shaffer, Tiffany Hamm
  • Brown University – Jane Carter