Leucine-zipper (bZIP) -family: common DBD-structure. 60-80 aa motif found in many dimeric TFsPrototypes: GCN4, Fos, Jun, C/EBP, ATF, CREBseveral possible dimer-partners ? numerous combinationsrapid equilibrium ? combinations determined by abundanceDimer-formation through parallel coiled coils of ?-helices (ZIP)each 7.aa = Leu3.5 aa per turn (coiled coil) ? each 7.aa in equivalent positionsAll Leu on same side ? dimerization through
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