SHIP1 deficiency in IBD. Sandra Fernandes 1 , James C. Ryan 2 , William G. Kerr 1 1 SUNY-Upstate Medical University, Syracuse, NY 2 UCSF/SFVA, San Francisco, CA Friday, December 13, 2013. DISCLOSURES. Nothing to disclose. SHIP1 and PI3K / Akt pathway. Fernandes & al., 2013.
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Sandra Fernandes1, James C. Ryan2, William G. Kerr1
1SUNY-Upstate Medical University, Syracuse, NY
2UCSF/SFVA, San Francisco, CA
Friday, December 13, 2013
Fernandes& al., 2013
Germline SHIP1-deficiency cause fatal eosinophilic pneumonia and Crohn’s-like ileitis in mice
For more on SHIP1 and mucosal inflammation in mouse model, please visit poster P-188
Kerr & al., GUT, 2011
SHIP1 : P1C1 + goat anti-mouse HRP, Actin : C-19 + donkey anti-goat HRP, Santa Cruz Biotechnologies
Modified from Grabbe & al. 2011
Ameres & Zamore, 2013