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Introduction to Oral Cancer Gene Database

Introduction to Oral Cancer Gene Database. ．資訊三 朱民晃 B92902025 ．資訊三 陳皓遠 B92902062. The Tumor Gene Family Databases. Introduction(1/2). http://www.tumor-gene.org/

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Introduction to Oral Cancer Gene Database

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  1. Introduction to Oral Cancer Gene Database ．資訊三 朱民晃 B92902025 ．資訊三 陳皓遠 B92902062

  2. The Tumor Gene Family Databases

  3. Introduction(1/2) • http://www.tumor-gene.org/ • The Tumor Gene Family of Databases contains information about genes which are targets for cancer-causing mutations; proto-oncogenes and tumor supressor genes. • These databases are designed to for biomedical researchers who work with tumor genes.

  4. Introduction(2/2) • Tumor Gene Database • Breast Cancer Gene Database • Oral Cancer Gene Database

  5. Oral Cancer Gene Database • What information dose the database contain? • This database contains information about genes which are targets for cancer-causing mutations in oral cancers. • List of Oral Cancer Genes • A member of the Tumor Gene Database family • http://www.tumor-gene.org/Oral/oral.html

  6. Get the list of Oral Cancer Genes (1/2) Click here to get information of the Oral cancer list

  7. Get the list of Oral Cancer Genes (2/2) • List of Oral Cancer Genes

  8. How to search the database (1/4) Key in a Gene Name or a word in a fact you want to search

  9. How to search the database (2/4) Click the “Search” button to search

  10. How to search the database (3/4) Get 1 match of the gene “BAX”Click the hyperlink of “BAX”

  11. How to search the database (4/4) OMIM ID Number of NCBI OMIM ID Number

  12. What can we get ? (1/2) • Cell Type Distribution • Clinical • Complementation • Function • Gene Frequency (Tumors) • Protein Binding • Regulation

  13. What can we get ? (2/2) Link to Citation of NCBI Flag

  14. Flags • Primary Fact from a Full Paper • Primary Fact from an Abstract • Secondary Fact from a Full Paper • Secondary Fact from an Abstract • Primary Fact from a Review • Secondary Fact from a Review • Unknown

  15. Link to GeneCards (1/2) Click here to link to GeneCards website

  16. Link to GeneCards (2/2)

  17. NCBI – OMIM (1/4) Remember to choose “OMIM” *600040 , the OMIM ID Number

  18. NCBI – OMIM (2/4) Click here; go to the OMIM homepage. Click “FAQ” to get details about OMIM

  19. NCBI – OMIM (3/4) What do the symbols preceding a MIM number represent?

  20. NCBI – OMIM (4/4) Ex: An asterisk (*) before an entry number indicates a gene of known sequence.

  21. Conclusion • We can search the information about oral gene in the database. • We can get the OMIM ID about the gene in the NCBI database. • We can get the list of genes in the oral database. • We can link to GeneCards website.

  22. Thanks for your attention.

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