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  1. A C 5000 2500 Events 10.0 7.5 TLR-2 (mfiI) 5.0 2.5 0.0 COPD Never AECOPD Smokers smokers 7.5 100 101 102 103 TLR-2 (mfi) 5.0 B TLR-4 (mfi) 2.5 5000 2500 Events 0.0 COPD AECOPD Smokers Never smokers 600 400 CD14 (mfi) 200 0 100 101 102 103 COPD AECOPD Smokers Never TLR-4 (mfi) smokers