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An Introduction to Systematic Reviews. Shakila Thangaratinam Professor of Maternal and Perinatal Health Women’s Health Research Unit R & D Director of Women’s Health Barts Health NHS Trust. Systematic review. What is it?. Traditional reviews. Search and acquisition of evidence not clear

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An introduction to systematic reviews

An Introduction to Systematic Reviews

ShakilaThangaratinam

Professor of Maternal and Perinatal Health

Women’s Health Research Unit

R & D Director of Women’s Health

Barts Health NHS Trust


Systematic review
Systematic review

  • What is it?


Traditional reviews
Traditional reviews

Search and acquisition of evidence not clear

Personal interests of the authors

Reliability issues


What is a systematic review
What is a systematic review?

Systematic undertaking of a review with a focused research question that tries to identify, appraise, select and synthesise all high quality research evidence relevant to that question. 


Systematic reviews
Systematic reviews

  • What is it?

  • Why do we need it?


Why do we need systematic reviews
Why do we need Systematic reviews

  • New evidence changes patient management

  • Delay in implementation can harm patient.

  • It is difficult to get evidence when it is needed

  • Knowledge and clinical performance deteriorates with time without an attempt to keep up-to-date

  • Traditional continuing education programs do not improve clinical performance

  • EBM keeps its practitioners up-to date


Why do systematic reviews
Why do systematic reviews?

Support Evidence Based Practice

Research

Inform clinical policy

Publication

Personal professional development


Systematic reviews

  • Review of reviews

Survey of practice

Yes

No

Primary studies

Good quality reviews

Poor quality reviews

Yes

No

Conduct Systematic reviews

Good quality study

Poor quality study

EBM

Design and conduct primary study


Systematic reviews1
Systematic reviews

  • What is it?

  • Why do we need it?

  • How to do them?


How to do systematic reviews
How to do systematic reviews?

Formulate clear clinical questions from our knowledge needs

  • Search the literature to identify relevant articles

  • Critically appraise the evidence for its validity and usefulness

  • Synthesise evidence


Workshop objectives
Workshop Objectives

  • Aim: Familiarisation with Systematic reviews

  • Objectives:

    • Literature Retrieval

    • Critical Appraisal of:

      • Therapy and Diagnosis

      • Primary studies and Systematic Reviews

    • Use of clinically meaningful statistics


The systematic review process

Search bibliographic databases

Design search strategy

Formulate research question

The systematic review process

Further selection of primary studies using inclusion criteria

Identify possible papers from titles/abstracts

Retrieve papers

Formulate research /

policy conclusions

Quality appraisal

Synthesis

Extract data


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