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Pathway Networks - PowerPoint PPT Presentation


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Pathway Networks. The following pictures indicate how the models associated the different pathways. The larger the arrow connecting two pathways, the greater the correlation, according to the p-values. Random Forest. Comparing Pathway 1 and 2. MAP Kinase. Huntington's Disease. Glutathione.

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Presentation Transcript
slide1

Pathway Networks

The following pictures indicate how the models associated the different pathways.

The larger the arrow connecting two pathways, the greater the correlation, according to the p-values.

slide3

Random Forest

Comparing Pathway 1 and 2

MAP Kinase

Huntington's Disease

Glutathione

TCA

Proteasome

Cell Adhesion

tRNA

Cell Cycle

PI Kinase

Porphyrin

Ribosome

Glycerolipid

Val/Leu/Ile

Purine

Oxidative Phosphorylation

Polymerase

-log p-values

Significant p-value= 4

Legend

Primary

Secondary

17

2 - 3

0 - 1.3

1.3 - 2

5 - 7

Red

Not a primary pathway

Not a pathway Correlation in Neural Networks