So, what is a Migraine Headache?. Migraine Definition. At least 2 of the following: Moderate to severe pain One sided Throbbing or pulsating in character Worsening with movement or bending over & At least one of the following:
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At least 2 of the following:
At least one of the following:
Beverly Hills, CA October 15, 2010 William J. Binder M.D., F.A.C.S. Inc., Beverly Hills plastic surgeon and pioneer in the cosmetic (anti-wrinkle) and therapeutic use of the BOTOX® neurotoxin, made headlines in the early 1990’s by discovering that BOTOX was effective in relieving the pain and preventing the onset of migraine headaches. Friday the U.S. Federal Drug Administration (FDA) approved BOTOX injections as a preventative treatment for chronic migraine sufferers.
Please see Important Safety Information, including Boxed Warning, throughout this deck.BOTOX® for Chronic Migraine Patients: Recommended Order of Injection* per Phase 3 Injection Paradigm1
* Recommended order of injection based on phase 3 injection paradigm; table in prescribing information differs.** Each IM injection site = 0.1 mL = 5 Units BOTOX®. † Dose distributed bilaterally.
Dosing and results in these studies are specific to the formulation of BOTOX® manufactured by Allergan, Inc. (Irvine, CA). The Allergan, Inc., formulation is not interchangeable with other botulinum toxin products and cannot be converted using a dose ratio.
Patient is in supine position2
Patient is in sitting position2
1. BOTOX® (onabotulinumtoxinA) Prescribing Information. Allergan, Inc., 2011.
2. Blumenfeld AM et al. Headache. 2010;50:1406-1418.