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A BREAKTHROUGH GENETIC APPROACH TO ANTI-AGING

A BREAKTHROUGH GENETIC APPROACH TO ANTI-AGING. SCIENCE IS THE ENGINE DRIVING NSE’s INNOVATION. Over 100 Full-Time Scientists - Many Disciplines Nutrition, Medicine Pharmacology, Biochemistry, Dietetics, Toxicology, Immunology, Physics, Biomedical Engineering

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A BREAKTHROUGH GENETIC APPROACH TO ANTI-AGING

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  1. A BREAKTHROUGH GENETIC APPROACH TO ANTI-AGING

  2. SCIENCE IS THE ENGINE DRIVING NSE’s INNOVATION • Over 100 Full-Time Scientists - Many Disciplines Nutrition, Medicine Pharmacology, Biochemistry, Dietetics, Toxicology, Immunology, Physics, Biomedical Engineering • Dr. Joseph Chang - Chief Scientific Officer Photodynamic Cancer Therapy Drug (Brain Tumors) Etodolic (Arthritis Drug) Rapamune (Anti-Rejection Drug) • Research Partners - Purdue University, Life Gen Technologies, Stanford University, Harvard University • Anti-Aging Scientific Advisory Board - 20 Scientists • 3 Global Research Centers Power NSE’s Research and Development Engine

  3. Beijing Clinical Center Provo, Utah Headquarters & Pharmanex Research Institute Shanghai R&D Center Huzhou Mfr. Plant Over 100 Scientists

  4. NSE IS THE ONLY SCIENCE-BASED COMPANY WITH 2 ANTI-AGING PRODUCT BRANDS ageLOC Skin Care = ageLOC OUTSIDE ageLOC Nutritionals = ageLOC INSIDE

  5. PHARMANEX SCIENCE + NU SKIN GUARANTEE: QUALITY INNOVATION SAFETY SUBSTANTIATED CLAIMS

  6. 25 Successful Years Publicly Traded on NYSE (NUS) Dunn & Bradstreet 5A1 Rating Operating in 50 Countries $1.3 Billion in Annual Sales 2009 2010 Projected Annual Sales Over $1.6 Billion = 23% Increase! Over $770 Million in Assets Over $180 Million in Cash Over $350 Million Spent on R&D Recognized & Featured in Numerous Media, Including Forbes Magazine & Investors Business Daily NSE – THE COMPANY BEHIND ageLOC

  7. NU SKIN—YOUR TRUSTED PARTNER +19% Top 5 Mid-Cap Company

  8. WHAT IS ? • A BREAKTHROUGH GENETIC APPROACH TO ANTI-AGING • A PLATFORM OF INNOVATIVE ANTI-AGING SOLUTIONS THAT TARGET AGE-RELATED GENES = THE ULTIMATE SOURCES OF AGING

  9. THE GENE REVOLUTION 1953: James Watson and Francis Crick identify the structure of the DNA molecule 2003: The Human Genome is sequenced & the map is completed 2010: An entire new branch of science emerges 9

  10. GENE SCIENCE IS THE HOT TOPIC IN THE MEDIA

  11. Old Paradigm: There is nothing you can do to influence your inherited genes and aging is inevitable. ageLOC Paradigm: Genes respond to the environment. Gene action & expression can be influenced and be restored to a more youthful state through targeted ingredient introduction.

  12. GENESIS OF AGELOC Identification of age-related genes by pioneers of aging research Exclusive collaboration with LifeGen to develop gene-based anti-aging products ageLOC creates a sustainable competitive advantage with exclusive access to over 30 years of research into the genetic basis of aging.

  13. SCIENCE SIMPLIFIED • IDENTIFY groups or clusters of genes which impact aging and understand their youthful expression patterns (Youth Gene Clusters or YGC’s); • ISOLATE - Investigate the aging effect of different ingredients on specific YGC’s in human tissues; • RESET - Develop formulae that reset these YGC’s back to their youthful state.

  14. ageLOC BALANCES YGC ACTIVITY Genes that ACCELERATE aging Genes that promote YOUTH

  15. Is it Safe to Influence Genes? X-MEN ageLOC is NOT: gene therapy genetic engineering gene splicing ageLOC IS: Nu Skin’s novel approach to developing products designed to support youthful gene expression.

  16. ageLOC SCIENCE VALIDATED Genetics of Aging Symposium University of Tokyo

  17. Stimulant-free cellular energy

  18. A MASS MARKET PRODUCT EVERYONE WANTS AT A PRICE EVERYONE CAN AFFORD! ageLOC science applied to internal body tissues – heart, brain & muscle tissues Influences genetic expression through targeted nutritional supplementation Clinically proven to increase PHYSICAL ENERGY, MENTAL ACUITY & SEXUAL DESIRE Only $50 for a month = $1.66/day!!!

  19. IS NOT - A stimulant, drug, or chemicals IS - A proprietary BLEND of mushroom, ginseng, and pomegranate (a fruit, a root & a fungus) that have been thoroughly studied and proven safe, combined in clinical doses to influence our genetic expression IS - The result of 30+ years of research by hundreds of doctors & scientists, multiple patents, and hundreds of millions of dollars in R&D

  20. MITOCHONDRIA: A KEY SOURCE OF YOUTHFUL VITALITY Mitochondria are the cellular power plants that convert energy from food (Kcals) into a form of energy our cells can use—ATP ATP fuels all biological functions With age, mitochondria number and efficiency declines dramatically Mitochondria dysfunction leads to age-related vitality loss

  21. MITOCHONDRIA HIGHLY CONCENTRATED IN: Brain Heart Muscle

  22. LATEST ageLOC DISCOVERY: ageLOC SCIENCE DISCOVERS THE GENETIC MECHANISM TO OPTIMIZE MITOCHONDRIAL POWER GENERATION Identified and influenced52 genes tied to mitochondrial function

  23. RESTORE YOUTHFUL VITALITY ageLOC Vitality targets the sources of age-related vitality loss by promoting youthful expression of mtYGC.

  24. BOTTOM LINE RESULTS Increased and sustained baseline ENERGY levels with NO stimulant effect Increased mental clarity, focus, ability to concentrate & productivity Increased libido More restful sleep and refreshed mornings Increased endurance & strength Better food choices & less appetite Regulated blood sugar Fewer aches and pains

  25. Energy drink market = $14 Billion!

  26. A Global Consumer Need NO COMPARISON

  27. $1.66 per day Demographic agnostic Increases energy and mental clarity Results in 7-12 days NO stimulants Price friendly - $50 for 180 capsules Available NOW in 6-packs!!! Will be available individually at the launch in January 2011

  28. GENE-BASED ANTI-AGING FROM THE OUTSIDE IN

  29. Anti-Aging Innovation Reducing the Size of Technology Download Media iTunes Store Proprietary Device with Consumable Gels & Complementary Products

  30. ageLOCGalvanic Spa System II Instant Results – Unique, Emotional, Affordable! • Smoothes Lines and Wrinkles • Lifts and Increases Skin Firmness • Micro Cleanses Skin to Dermal Layer • Improves Skin Texture and Pore Size • Treatment Takes Only 5 Minutes 2-3/wk! Hand-held Patented Technology

  31. Reduce the Visible Signs of Aging

  32. VALUE Galvanic ageLOC Spa Package = $290 • Galvanic Spa Device – Can be used with ANY daily skin care regimen • 4 Interchangeable Heads • 8 Sets of Facial Treatment Gels (1 month) • 1 NaPCA Moisture Mist (1 month) • Cost per Treatment (after 1st 8 treatments)= $7.50!!!

  33. The Most Advanced Product in Nu Skin History! FUTURE SERUM • Maximum concentration of ageLOC ingredients • ageLOC & other anti-aging ingredients clinically proven to significantlyimprove skin in 8 ways

  34. Four YGCs Identified That Are Responsible for 8 Signs of Skin Aging 8 Signs of Aging Fine Lines & Wrinkles Youth Gene Clusters Youthful SkinStructure Discoloration Skin Tone Hydration Texture, Smoothness Radiance Pore Size

  35. ageLOC Results

  36. VALUE FUTURE SERUM • Can be used with ANY daily skin care regimen • Twice daily application • $157 for 30 day supply • Compare to leading anti-aging serums: • Chanel – Subimage = $400.00 • Estee Lauder – Re-Nutriv = $140.00 • Lancome – Secret De Vie = $265.00 • La Prairie – Radiance Collection =$570.00

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