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Gene Expression Changes in Response to 40 mM 3AT Treatment in Prokaryotic Systems

This study analyzes the differential gene expression in specific mutants and conditions, focusing on the GCN2 and GCN4 pathways. We observed significant up-regulation and down-regulation of genes in response to 40 mM 3AT treatment. The findings highlight the adaptive mechanisms of cellular responses to stressors and may provide insight into the regulatory functions of GCN pathways. The assessment of gene expression variations will facilitate a better understanding of gene regulation in prokaryotes and their responses to metabolic perturbations.

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Gene Expression Changes in Response to 40 mM 3AT Treatment in Prokaryotic Systems

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  1. Down in gcn2 Down in gcn4 Up in gcn4 Down in CAF2-1 Up in CAF2-1 14 7 224 168 18 7 7 15 160 65 0 5 77 27 Up in gcn2 Significantly up-regulated genes in response to 40 mM 3AT Significantly down-regulated genes in response to 40 mM 3AT

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