Autoimmune Epilepsies. Azhar Daoud , MD, FRCP Professor and Consultant in Child Neurology, Specialty Hospital, Amman, Jordan. Anticonvulsant activity of steroids Fever and infection exacerbate seizures Seizures frequency in autoimmune diseases
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AzharDaoud, MD, FRCP
Professor and Consultant in Child Neurology, Specialty Hospital,
Antibodies directed against molecules on the neural surface, e.g. N-methyl-D-aspertate receptor (NMDA-R) or the voltage gated potassium channel(VGKC) complex
Limbic encephalopathy and temporal lobe seizures (subacute onset of sever memory impairment and mood disturbance with recurrent temporal lobe seizures)
Acute psychiatric disorders(delirium, visual or auditory delusions, aggression and irritability) and epileptic seizures, usually of extratemporal origin, initial phase followed by
Rasmussen’s encephalitis, hemispheric brain inflammation leading to unilateral brain atrophy, viral infections
IHHS, febrile seizures followed by hemiplesia started as flaccid before becoming progressively spastic
Fever trigger status epileptics, clonic jerks or head and eye deviation, predominant in one side and last for several hours
The finding of inflammatory markers and especially autoantibodies in several epileptic disorders of unknown etiology has open up a group of possible causes and investigations in epilepsies.