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Chapter 5. 1040 Integumentary. Skin. ______ – superficial and thinner _____ – deeper and thicker ______ – areolar and adipose tissue Not technically part of the skin Aka subcutaneous layer Contains nerves, blood and fat Function of fat. Epidermis. _________________________ Why?

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chapter 5

Chapter 5

1040 Integumentary

slide2
Skin
  • ______ – superficial and thinner
  • _____ – deeper and thicker
  • ______ – areolar and adipose tissue
    • Not technically part of the skin
    • Aka subcutaneous layer
    • Contains nerves, blood and fat
      • Function of fat
epidermis
Epidermis
  • _________________________
    • Why?
  • Layers
    • Stratum basale – deepest
      • Single row of cuboidal or columnar
      • All stem cells are here
    • Stratum spinosum
      • Flatten and keratinize
    • Stratum granulosum
      • Lipid water repellent
      • More flat and more keratinized and beginning to die
    • Stratum corneum
      • Dead cells
layers
Layers
  • Stratum ____________
    • Shedding layer – help protect against injur and invasion
dermis
Dermis
  • _________________ – why?
  • Has nerves and blood to feed it and epidermis
  • Sun exposure causes wrinkling by disrupting collagen and elastic fibers
melanin
Melanin
  • In basal layer
  • Same ________ of melanocytes in all people – skin color is based on melanin production
  • Accumulations of melanin
    • Liver spots and freckles
slide7
Hair
  • Fused dead keratinized cells
    • Keratin – tough protecting protein
  • Hair follicles have ____________
    • Hair stands on end
  • Has _____________ (oil)
  • Hair color – based on melanocytes
    • Gray – loss of melanin
    • Blond and red – more iron and sulfur in melanin
  • Alopecia
glands
Glands
  • ____sweat glands – located over most of the body
    • Regulates body temp
  • ____ sweat glands – armpit, groin, breast, beard
    • Begin function at puberty
    • Stimulated by stress and sex
nails
Nails
  • Hard, packed, keratinized epidermal cells
  • Cuticle is stratum corneum
  • ________ – white part due to thick stratum basale hiding vascular bed
  • Nail matrix – gives rise to new nail
skin function
Skin function
  • Temp regulation
  • Protection
  • Sensation
  • Excretion and absorption (garlic)
  • ______ synthesis
    • UV activates Vit D
      • Helps absorp calcium and phosphorus from GI tract
slide11

ABCD for melanoma

  • Asymmetry, border irregularity, color variegation, diameter >6mm.
    • Red, white, blue with notched border and has a papule or nodule w/in
    • 10% are missed w/ the ABCDs
  • Incr rate of occurrence faster than any other cancer in US
    • Ages 15-50yoa m/c
    • 1:90 chance of developing melanoma
    • Cancer of melanocytes
    • Risk factors: sunlight, heredity, large # of nevi, large nevi