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從身體活動角度 談代謝症候群的治療. 台北醫學大學.雙和醫院 復健醫學部 劉燦宏. Obesity Trends* Among U.S. Adults BRFSS, 1990, 1995, 2005. (*BMI 30, or about 30 lbs overweight for 5’4” person). 1995. 1990. 2005. No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%.
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從身體活動角度談代謝症候群的治療 台北醫學大學.雙和醫院 復健醫學部 劉燦宏
Obesity Trends* Among U.S. AdultsBRFSS,1990, 1995, 2005 (*BMI 30, or about 30 lbs overweight for 5’4” person) 1995 1990 2005 No Data <10% 10%–14% 15%–19% 20%–24% 25%–29% ≥30%
2001 Stumvoll M. et al. Lancet. 2005;365:333-346
造成肥胖日益嚴重的原因 • 活動量降低 • 肥胖基因 • 飲食習慣
黑色棘皮症 憂鬱症 腦中風 睡眠呼吸中止 心肌梗塞 高血壓 下背痛 糖尿病 、脂肪肝 退化性關節炎 末梢血管病變 痛風 肥胖的併發症
MRI 腹部縱剖面圖說明 體脂率 42.4% 臟器脂肪 皮下脂肪
MRI 腹部縱剖面圖說明 體脂率 27.5% 臟器脂肪 皮下脂肪
Fat stores Obesity Is Caused by Long-Term Positive Energy Balance Energy expenditure Energy intake
Treatment Pyramid Surgery Pharmacotherapy Lifestyle Modification Diet Physical Activity
~五百萬年 ~五十年 Human Evolution
Sedentary Behaviors and Metabolic Syndrome Bertrais et al. Obes Res 2005;13:936
Effect of Decreasing Sedentary Activities vs Increasing Physical Activities on Body Weight in Children 6-12 Years Old Increased Physical Activity Change in Percent Overweight Decreased Sedentary Activity 0 4 8 12 Time (months) Epstein et al. Health Psychol 1995;14:109.
MetS Risk Factors (RF) Vs. METs Rana et al. Int J Cardiol. 2006;110:224
Mean WBC Vs. METs & MetS Risk Factors Rana et al. Int J Cardiol. 2006;110:224
Association of Muscular Strength with Incidence of Metabolic Syndrome in Men • Jurca et al. Med Sci Sports Exerc 2005;37:1849
Exercise Recommendations for Weight Loss 1. 減少慢性病發生的建議量 --每天至少30分鐘的中等強度運動 2. 減肥或維持體重的建議量 --每天60分鐘的中等到激烈強度的運動 3. 減肥後的體重維持或要繼續減肥 --每天60~90分鐘的中等到激烈強度的運動 Saris WH et al. Obes Rev. 2003;4:101-114.
Considerable Physical Activity is Necessary for Weight Loss Maintenance Concomitant Behavior Therapy Weekly Biweekly Monthly <150 min/wk Change in Weight (kg) >150 min/wk *P<0.05 >200 min/wk 0 6 12 18 Time (months) Jakicic et al. JAMA 1999;282:1554.
Definition • Physical activity, is any bodily movement produced by the contraction of skeletal muscles resulting in caloric expenditure, includes LTPA and OPA. • Exercise, is a sub-category of physical activity and is activity which is planned, structured and repetitive.
Metabolic Calculations • BMR=BM × 24 × 1.05 kcal/day (H-B equation or indirect measure maybe needed for specific individuals) • TEE = BMR × activity factor • activity factor = 1.2 for sedentary • activity factor = 1.4 for moderately active • Based on energy deficit of 1,000 kcal/day • Diet control = TEE – 600 kcal/day • Exercise prescription = 400 kcal/day or 2,800 kcal/wk
Losing Weight through Structured Exercise • Pre-test screen (PAR-Q) • Chronic condition • Build up gradually for sedentary individuals • Cross train to reduce overuse injuries • Exercise prescription for weight loss • Primary cardiovascular (aerobic) activities • 200-300 min per week or >2000 kcal/wk • 55-70% of maximal heart rate
Exercise Prescription Safety Burn energy
Exercise Prescription • What intensity? • Too low • Takes too long to achieve energy expenditure target • Inadequate stimulus for aerobic fitness • Too high • Premature cessation of exercise • 55-70% of HRmax • How frequent? • At least 5 days/wk • 7 days/wk for diabetics
Relationship Between Physical Activity and Maintenance of Weight Loss P<0.001 Subjects Exercising (%) Not Maintained Maintained Weight Loss Pattern
Improving Long-term Adherence to Physical Activity (NWCR) • Short bouts • Home exercise equipment • Small incentives • Pedometers • Group and supporter
Behavioral Strategy in Weight Maintenance (NWCR) • Extended contact • Clinical visit • Phone call • Internet • Social support • Problem solving and Relapse prevention
Monitoring the Calories • Energy expenditure table (manual/PDA/ websites) • Cardio machines (RFID) • HR monitors • 2D or 3D accelerometer • Pedometers
Exercise Recommendations for Increase of Physical Activity • Assessment 1) Medical and psychological readiness (PAR-Q) 2) Physical limitations (eg. knee OA, poor fitness etc.) 3) Current activities 4) Barriers to activity • Develop physical activity plan, LTPA or OPA • Start activity slowly and gradually increase planned aerobic activity to 300 min/wk • Enhance compliance • Programmed vs lifestyle activity • At-home vs onsite activity • Multiple short bouts vs single long bout of activity
Thanks for Your Attention 台北醫學大學.雙和醫院 復健醫學部 劉燦宏