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Each human cell contains the same genetic information. The human body consists of many different cell types. Nerve cell. Muscle cell. Red blood cell. There are thousands of proteins in a human body, proteins make the difference between cells.
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The human body consists of many different cell types Nerve cell Muscle cell Red blood cell
There are thousands of proteins in a human body, proteins make the difference between cells
Cells translate genetic information into proteins There are about 20,000 genes – genes are the blueprint for proteins Cells translate genetic information into proteins So far more than 18,000 proteins have been mapped
Protein research 20 years ago Piece of a liver Information on one protein Extraction ofone protein High biochemical effort
Protein research today: Proteomics Different organs and tissues Chromatography and mass spectrometry Extraction of all proteins Dataanalysis Database ProteomicsDB Information on many proteins https://www.proteomicsdb.org
What can we learn from proteomes? Proteomics helps us understanding health and disease Proteomics helps us understanding human biology Healthy Brain tumor Some proteins are only required in certain organs Proteomics helps us finding the right treatment for a disease Patient A Patient B Treat with drug B Treat with drug A
Sources: • H. Hahne, B. Wankerl/TUM • Dorling_Kindersley/iStock (slide 1+2) • johnwoodcock/iStock (slide 1+4) • alex-mit/iStock (slide 1) Contact: Technische Universität München Corporate Communications Center Barbara Wankerl barbara.wankerl@tum.de Phone: +49 89 289 22562