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Unravel the mysteries of pedigree analysis to determine inheritance mode, offspring probability, and understand genetic symbols like nondisjunction. Explore autosomal dominant & recessive, sex-linked traits with practical examples.
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Goals of Pedigree Analysis • 1. Determine the mode of inheritance: autosomal dominant & recessive, sex-linked, etc. • 2. Determine the probability of an affected offspring for a given cross.
Nondisjunction • the failure of one or more pairs of homologous chromosomes or sister chromatids to separate normally during meiosis – uneven distribution of chromosomes in eggs or sperm.
Recessive Sex-Linked • Draw for DMD