SA2125

1. Carbamate H2O HCO3– + NH4+ HCO3– + L-Glutamine ADP + Pi 2 ATP ATP HCO3– + NH4+ Urea Mg2+ PyrAA GlnA UreABC SA1013 Mg2+ PyrAB ArcC ATP 2 ADP + Pi L-Glutamate H2O ADP NH4+ L-Arginine (extracellular) L-Ornithine Carbamoyl phosphate Formamide ArcD SA2125 PyrB L-Ornithine (extracellular) ArgF ArcB Arg L-Aspartate Pi Pi N-Formimino-L-glutamate H2O N-Carbamoyl-L-aspartate L-Arginine L-Citrulline ArcA HutI PyrC H2O ArgG L-Arginino-succinate ATP ArgH (S)-Dihydroorotate 4-Imidazolone-5-propanoate Fumarate O2 AMP + PPi HutU SA2375 H2O2 ATP ADP + Pi ATP ADP ATP AMP Orotate Urocanate RbsD Mg2+ Mg2+ D-Ribose (extra- cellular) D-Ribose-5- phosphate 5-Phosphoribosyl-1-Pyrophosphate D-Ribose HutH RbsK Prs PyrE RbsU PPi Histidine Orotidine-5-phosphate PyrF PPi H+ (extracellular) H+ CO2 Upp Uridine monophosphate (UMP) Uracil (extracellular) Uracil PyrP PyrR ATP Deoxy-D-Ribose- 1-phosphate Cmk Mg2+ DeoD Pnp ADP Pi UDP ATP Deoxyuridine Mg2+ Ndk ADP UTP L-Glutamine + H2O + ATP CtrA Mg2+ Transcription enhanced in BB1305 L-Glutamate + ADP + Pi Transcription reduced in BB1305 CTP