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Ohio Center of Excellence on Knowledge-Enabled Computing (Kno.e.sis). Ohio Center of Excellence on Knowledge-Enabled Computing (Kno.e.sis ). scientia potentia est Knowledge is Power Francis Bacon, 1597 …established and popularized deductive methodologies for scientific inquiry.

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slide2

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

scientiapotentiaest

Knowledge is Power

Francis Bacon, 1597

…established and popularized deductive methodologies for scientific inquiry

slide3

Ohio Center of Excellence

Knowledge-Enabled Computing (Kno.e.sis)

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

Our society has progressed from

Agriculture

Industrial

Service

Knowledge

… we live in a Knowledge Society

slide4

Knowledge Economy

As the economies have transformed ….

… new era … where the principal component of

value creation, productivity and economic growth is

knowledge. Florida & Kenny 91

slide5

Knowledge Economy

Thousands

knowledge-intensive services are leading the all sector in job creation, R&D spending, average wages and growth.

slide6

affects

Migraine

Magnesium

Stress

inhibit

isa

Knowledge discovery

Patient

Calcium Channel

Blockers

2D-3D & Immersive Visualization, Human Computer Interfaces

Impacting bottom line

Domain Models/Knowledge

Structured text (Scientific publications / white papers)

Biomedical Knowledge Discovery,

Knowledge

Management & Visualization

SEMANTICS, MEANING PROCESSING

Patterns / Inference / Reasoning

Meta data / Semantic Annotations

Search and browsing

Metadata Extraction/Semantic Annotations

Massive amounts of data

Clinical Trial Data

Experimental

Results

Public domain knowledge (PubMed)

slide7

Kno.e.sis Vision

Kno.e.sis’ leadership in semantic processing will contribute to basic theory about computation and cognitive systems, and address pressing practical problems associated with productive thinking in the face of an explosion of data.

Kno.e.sis intends to lead a march from information age to meaning age.

slide8

Why Kno.e.sis?

  • We have exciting vision built on cutting edge research and technology
  • We incorporate synergy to carry out exceptional vision
  • We are world class – and recognized as such
  • Our track record shows we can succeed
  • We target the growth aspect of economy and regional/state needs
slide9

Globally Competitive Careers and Economic Development

WPAFB Directorates

Dayton Region Companies

Human Effectiveness

Sensor

Woolpert

REI Tech, Aptima

Tech^Edge

SAIC

LexisNexis

Knowledge Workers, Products, Services and Applications

Defense/Aerospace R & D

Advanced Data Management

Human Sciences

& Health Care

Application to Regional Industry Cluster

Kno.e.sis+Faculty Strengths

daytaOhio – a WCI

  • Cognitive Science & Human Factors
  • Data Analysis/Mining/Visualization
  • Info. & Knowledge Mgmt
  • Web 3.0 (Semantics, Services, Sensors)
  • Virtual Worlds, Social Computing
  • High Performance/Cloud Computing
  • Bioinformatics/Biomedicine, Healthcare
  • Visualization and Data Mgt Infrastructure
  • Consulting and Technology Transfer

Academic Research and Infrastructure

slide11

Significant Infrastructure

VERITAS

Whole-Body Laser

Range Scanner

stereoscopic 3D

visualization

NMR

AVL

slide12

Exceptional

  • Regional Collaboration
  • At least 6 active projects with AFRL/WPAFB
    • Human Effectiveness Directorate
    • Sensors Directorate
slide13

Exceptional

  • National Collaboration
  • Univ. of Georgia, Stanford, Purdue, OSU, Ohio U., Indiana U. UC-Irvine, Michigan State U., Army, W3C
  • Microsoft, IBM, HP, Google
slide14

Exceptional

International Collaboration

  • U. Manchester, TU-Copenhagen, TU-Delft, DERI (Ireland), Max-Planck Institute, U. Melbourne, U Queensland, NICTA-Australia,CSIRO, DA-IICT (India)
slide15

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

Knowledge & Next Generation of the Web

Web has become the core infrastructure for the knowledge economy

Web 1.0: Web of Documents and Media

Web 2.0: Web of People

Web 3.0: Web of Meaning

MeenaNagarajan

Advanced Data Management

knowledge extraction

KNOWLEDGE EXTRACTION

“Human Cognition” AND Psychology AND Neuroscience?

slide17

Harvesting Community Knowledge & Scientific Corpus

“Human Cognition” AND Psychology AND Neuroscience

slide18

Human Performance &

Cognition Ontology

slide20

DataExploration on the Web

Utilizes semantic information from domain models to guide user interaction

  • “PTEN protein could inhibit cell invasion even in the presence of ... epidermal growth factor receptor (EGFR)” [PMID: 15986432]
  • “EGF and hypoxia induce CXCR4 in non-small cell lung cancer...” [PMID:15802268]
  • Record navigation trail:
    • EGFR  induces  CXCR4
slide21

Cuebee and Scooner

Shared as open source, with demos online.

slide22

Ohio Center of Excellence

Knowledge-Enabled Computing

SEMANTIC SENSOR WEB

slide23

Semantic Sensor Web

Utilizes semantic technologies to bridge the divide between the “real-world” and the Web

Environment

Sensor

Observation

Physical World (“real-world”)

Information Space (Web)

Perception

Situation Awareness

Sensor Data

slide24

Semantic Sensor Web

  • Linked Sensor Data provides semantic descriptions for:
    • ~20,000 weather stations in the United States.
    • 160 million observations (~2 billion statements).
    • named locations that are nearby (in Geonames)

near

weather station

semantic social web

Ohio Center of Excellence

Knowledge-Enabled Computing (Kno.e.sis)

SEMANTIC SOCIAL WEB

everyone wants to talk and be heard
Everyone Wants to talk …and be heard!

Hundreds and thousands of tweets, facebook posts, blogs about a single event, multiple narratives, strong opinions, breaking news..

twitris twitter tetris
TWITRIS : Twitter+Tetris
  • Our attempt to help you keep up with citizen observations on Twitter
    • WHAT are people saying, WHEN, from WHERE
  • Puts citizen reports in context for you by overlaying it with news, wikipedia articles!
biomedical health sciences from data to understanding mike raymer

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

Many biomedical collaborations: Nick Reo, Toxicology; Tim Cope, Neuroscience;

Jerry Alter, Protein Science; Oleg Paliey, Microbiolgy and health

Many health care collaborations: Kate Cauley, Center for Healthy Communities; UC-Irvine – Emergency health, Sonia Michail, obesity & intestinal health; Bradley Jacobs, human health

Biomedical & Health Sciences

From data to understanding

Mike Raymer

Human Sciences

& Health Care

slide30

Biomedical & Health Sciences

From data to understanding

slide31

Computation & Life Science

  • Publication/Funding Trends

Perez-Iratxeta, C. et al. Brief Bioinform 2007 8:88-95; doi:10.1093/bib/bbl035

slide32

Biomedical & Health Sciences

From data to understanding

  • Toxicology
  • Neuroscience
  • Protein science
  • Pediatrics
  • Clinical psychology
  • Obesity
  • Krohn’s disease
  • Treating Schizophrenia
  • Emergency Health
slide33

Cross-disciplinary workHow we do it

  • Determine whether exposure has occurred
    • Including low-dose exposure
  • Predict downstream outcome
    • Organ/system toxicity vs. recovery
  • Using easily deployable tests
    • Blood, urine, etc.
slide35

Nationwide Health

CDC

VA

IHS

DoD

SSA

State and Local Gov

Health Bank orPHR Support Organization

Community Health Centers

Community #1

Labs

As part of Nationwide Health Information Network effort, Center for Healthy Communities (CHC) will use its HIExTM system, supported through Wright State HealthLink and medical providers to electronically transmit data from their certified EHRs to the Social Security Administration (SSA). This will improved quality of care through analysis of large data sets documenting treatments and outcomes. Knoesis will be in the forefront creating the systems intelligence to better understand this complex, integrated information both at the individual provider level and in the realm of population health. CHC received ~1M contact from SSA.

IntegratedDelivery System

Pharmacies

Community #2

slide36

Biomedical & Health Sciences

From data to understanding

Data

Information

Understanding

cognitive science applications to human effectiveness john flach

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

Cognitive Science & applications to Human Effectiveness

John Flach

Defense/Aerospace R & D

slide38

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

putting humans into control
Putting Humans Into Control

Samuel Pierpont Langley

slide46

Regional Impact

  • Collaboration by daytaOhio and the Dayton Development Coalition to Leverage Kno.e.sis
  • Terry Rapoch – President/CEO daytaOhio
  • Jim Leftwich – CEO Dayton Development Coalition
slide47

Regional Development Model

Knoesis

Advanced Data Analysis

slide48

Collaboration Objectives

  • Complement the knoesis Center in two ways that are consistent with daytaOhio’s vision and regional role
    • Expanding the scope of R&D into knowledge services
    • Identifying opportunities to commercialize the knowledge services developed by Kno.e.sis
  • Enhance the impact of Kno.e.sis on regional economic development
    • Attracting more research funding and talent
    • Providing commercial channel for knoesis innovations
    • Supporting knowledge base start ups
    • Bringing new products and service to existing businesses
slide49

Process

  • Continue to develop initial opportunities with LexisNexis
  • Catalog knoesis Intellectual Property available for commercialization
  • Qualify additional partners in the region working with Dayton Development Coalition
  • Expand role of knoesis in regional human centered innovation opportunities
slide50

Partners

  • AFRL/HPW-RHCB/WSU
  • SAIC
  • Sensor web
  • Kettering/Siemens
  • Image knowledge extraction
  • LexisNexis
  • Ontology, semantics browsers
  • Ohio IT Alliance/Point Energy Solutions
  • Knowledge extraction
  • Researchand development
    • Evaluation of systems and process using Virtual Reality
    • Integration of sensors into immersive visualizations
    • Medical – post processing of images into immersive environments
  • Commercial direction
    • Integration, knowledge services IP
    • Data center energy
board of advisor s view

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

Board of Advisor’s View

Prof. Ahmed Elmagarmid

Cyber Center – Discovery Park

Purdue University

slide53

Faculty

  • Over 2,000 citations per faculty, around 1,000 refereed publications – comparable to any excellent group; granted 74 PhDs, $50 million in cumulative funding
  • Prof. Sheth among the most cited Computer Science authors in the world today(top 30 based on h-index)
  • Prof. Bennett & Flach’s papers as one of most influential papers published in over 50 years in Journal of Human Factors; Prof. Raymer’s paper was cited in a US Supreme Court decision
  • Kno.e.sis has attracted top-notch faculty
  • High quality funding: NIH, NSF, AFRL…..innovation grants: Microsoft Research, Google, IBM Research, HP labs
  • Entrepreneurship experience – launched several companies
slide55

Funding

Starting with current active funds of $8-10 million (supporting research of 15 faculty and 45+ funded grad students & postdocs) Kno.e.sis anticipates growing to $13 million in 5 years and $19.5 million in 10 years (25 faculty plus 75 researchers)

slide56

World Class Students

  • Meena Nagarajan gave a keynote at an international workshop– unheard of for a PhD student
  • Satya, Cory, Karthikorganized international workshops
  • Six of the senior PhD students: 84 papers, 43 program committees, contributed to winning NIH and NSF grants.
  • LyubomirZagorchev, a recent alumni invited to give a talk at Harvard.
  • Students interned at & collaborated with the very best places: Microsoft Research, Yahoo! Research, IBM Research, HP Labs, NLM, …and filed for 6 patents in 2 years
slide57

Opportunities

  • and Challenges
  • Noteworthy
  • Possibly the largest or second largest academic research group in the US in Semantic Web (key enabled of Web 3.0)
  • Internationally recognized faculty
  • Demonstrated ability to prepare world class students
  • Regional, National and International Collaborations and Leadership (eg W3C)
  • Recognition of the opportunity from the University leadership
  • Adequate but will need to grow to support growth
  • Infrastructure (computing, space)
  • Institutional/State Support: administrative and business support (e.g., grant writing), Faculty lines
  • Continued effort to attract best local, US and international students
slide58

Metrics

  • How we propose to benchmark/evaluate the progress?
  • Recognition & Visibility (be #1, 2, or 3 in US)
  • Funding (200% of averages in respective unit; over average of COE’s at tier 1 institutions)
  • Student Achievements (15 to 20% above national &regional averages for salaries, placement in top 20% of high value jobs)
  • Faculty Achievements (publications at 200% of respective units)
  • Collaborations
  • Economic Impact