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The Normal Distribution

The Normal Distribution. Objectives: For variables with relatively normal distributions: Students should know the approximate percent of observations in a set of data that will fall between the mean and ± 1 sd , 2 sd , and 3 sd

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The Normal Distribution

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  1. The Normal Distribution Objectives: For variables with relatively normal distributions: • Students should know the approximate percent of observations in a set of data that will fall between the mean and ± 1 sd, 2 sd, and 3 sd • Students should be able to determine the range of values that will contain approximately 68%, 95%, and 99% of the observations in a set of data.

  2. The Normal Distribution (also called the bell-shaped or Gaussian distribution)

  3. The Normal Distribution • The normal distribution is completely defined by the mean and standard deviation of a set of quantitative data: • The mean determines the location of the curve on the x axis of a graph • The standard deviation determines theheight of the curve on the y axis There are an infinite number of normal distributions- one for every possible combination of a mean and standard deviation

  4. Examples of Normal Distributions Pr(X) on the y-axis refers to either frequency or probability.

  5. Examples of Normal Distributions

  6. Normal Distributions Many (but not all) continuous variables are approximately normally distributed. Generally, as sample size increases, the shape of a frequency distribution becomes more normally distributed.

  7. Frequency of occurrence Normal Distributions When data are normally distributed, the mode, median, and mean are identical and are located at the center of the distribution.

  8. Skewness Quantitative variables may also have a skewed distribution: When distributions are skewed, they have more extreme values in one direction than the other, resulting in a long tail on one side of the distribution. The direction of the tail determines whether a distribution is positively or negatively skewed. A positively skewed distribution has a long tail on the right, or positive side of the curve. A negatively skewed distribution has the tail on the left, or negative side of the curve.

  9. Skewed Distributions Normal distribution Positively skewed distribution Negatively skewed distribution

  10. Range of Observations For a normally distributed variable: ~68.3% of the observations lie between the mean and  1 standard deviation ~95.4% lie between the mean and  2 standard deviations ~99.7% lie between the mean and  3 standard deviations

  11. Heart Rate Example For the heart rate data for 84 adults: Mean HR = 74.0 bpm SD = 7.5 bpm Mean  1SD = 74.0  7.5 = 66.5-81.5 bpm Mean  2SD = 74.0  15.0 = 59.0-89.0 bpm Mean  3SD = 74.0  22.5 = 51.5-96.5 bpm

  12. +3 SD +2 SD + 1SD Mean -1 SD -2 SD -3 SD Heart Rate Example HR Data: 57/84 (67.9%) subjects are between mean ± 1SD 82/84 (97.6%) are between mean ± 2SD 84/84 (100%) are between mean ± 3SD

  13. Reference (“Normal”) Ranges in Medicine The “normal” range in medical measurements is the central 95% of the values for a reference population, and is usually determined from large samples representative of the population. The central 95% is approximately the mean  2 sd* Some examples of established reference ranges are: Serum“Normal” range fasting glucose 70-110 mg/dL sodium 135-146 mEq/L triglycerides 35-160 mg/dL Note: The value is actually 1.96 sd but for convenience this is usuallyrounded to 2 sd.

  14. The Standard Normal Distribution A normal distribution with a mean of 0, and sd of 1  The distribution is also called the zdistribution Any normal distribution can be converted to the standard normal distribution using the z transformation. Each value in a distribution is converted to the number of standard deviations the value is from the mean. The transformed value is called a z score.

  15. Formula for the z transformation Once the data are transformed to z-scores, the standard normal distribution can be used to determine areas under the curve for any normal distribution.

  16. Example of a z-transformation If the population mean heart rate is 74 bpm, and the standard deviation is 7.5, the z score for an individual with HR = 80 bpm is: The individual’s HR of 80 bpm is 0.8 standard deviations above the mean.

  17. Rule of Thumb #1 The z-value can be looked up in a table for the standard normal distribution to determine the lower and upper areas defined by a z-score of 0.8 (the areas are the lower 78.8% and upper 21.2%) You will not need to calculate z-scores or find corresponding areas under the curve for z-scores in this class, but you will be expected to know the following: The important z-scores to know are ±1.645, ±1.960*, ±2.575 Note: when calculating by hand, it is OK to round 1.960 to 2

  18. Rule of Thumb #2 The total area under the normal distribution curve is 1: 90% of the area is between ± 1.645 sd 95% of the area is between ± 1.960 sd 99% of the area is between ± 2.575 sd

  19. The Normal Distribution & Confidence Intervals 90% of the area is between ± 1.645 sd 95% of the area is between ± 1.960 sd 99% of the area is between ± 2.575 sd These are the most commonly used areas for defining Confidence Intervals which are used in inferential statistics to estimate population values from sample data

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