Wegener’s Granulomatosis. Kelly Mitchell July 5, 2006 Morning Report. History of Wegener’s. In 1931, two patients died from prolonged sepsis with inflammation of blood vessels scattered throughout the body.
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July 5, 2006
* For purposes of classification, a patient shall be said to have Wegener's granulomatosis if at least 2 of these 4 criteria are present. The presence of any 2 or more criteria yields a sensitivity of 88.2% and a specificity of 92.0%
Symptom At Onset Total
One-third of patients may be without symptoms at onset of disease
Criteria for Classification
(Only large sections of lung tissue obtained via thoracoscopic or open lung biopsy are likely to show all of the histologic features)
However, 50% in remission relapse
AND daily cyclophos is very toxic