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778del T FS. l698X. R499X. Q769X. R554X. R803X. Y486X. R564X. Y935X. W157X. 1464del AG FS. Q1338X. S713X. Q218X. Q1067X. Q541X. Q208X. APC Protein domains. Codons. 1000. 700. 1300. 2000. 2400. 2842. R414C. G1120E. S1234X. S1395C. C1272X. I1307K. 1244del G FS. E1317.

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  1. 778del T FS l698X R499X Q769X R554X R803X Y486X R564X Y935X W157X 1464del AG FS Q1338X S713X Q218X Q1067X Q541X Q208X APC Protein domains Codons 1000 700 1300 2000 2400 2842 R414C G1120E S1234X S1395C C1272X I1307K 1244del G FS E1317 168 1580 Classical FAP 1250 1464 severe FAP 1580 78 400 AAPC AAPC 1444 457 CHRPE 1395 2000 DESMOIDS 15 Amino acids repeat Homodimerization domain Microtubule binding domain 20 Amino acids repeat EB1 binding domain Armadilo repeat SAMP repeat PDZ binding domain

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