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2. Bacitracin Most active against G+ bacteria, including Staph. Producing B- lactamase & streptococci
Mechanism of action
Inhibition of cell wall synthesis
Clinical uses
Not used systemically
Topical for infections of mouth, nose, eye and skin
Available in an ointment ( often combined with polymixin or neomycin ) for suppression of mixed bacterial flora in skin, wounds or mucus membranes