Neural Basis of the Perception and Estimation of Time

1. Neural Basis of the Perceptionand Estimation of Time SE367 Homework 3

2. Previous works Scalar timing theory(Gibbon et al.1984)Neurophysiological model of timing(Matell & Meck 2004)

3. EVIDENCE FAVORING ACOMMON TIMING MECHANISM Work started in late 19th century Time dependent and time independent sourcesTemporal processing

4. EVIDENCE FAVORING AUBIQUITOUS TIMING ABILITYOF CORTICAL NETWORKS Timing is an inherent computational ability of every cortical circuit Psychophysical experiments suggest that sensory timing is local.

5. AN INTERMEDIATEHYPOTHESIS Merchant and colleagues (2008c)

7. NEUROPHYSIOLOGICAL BASISOF TIME ESTIMATION:RAMPING ACTIVITY IN THECORE TIMING CIRCUIT Most studies report climbing activity during a variety of timing tasks.

9. NEUROANATOMICAL ANDNEUROCHEMICAL SYSTEMSFOR INTERVAL TIMING The centrality of the striatum and dopamine (DA) neurotransmission in explicit timing. Frontoparietalsystems may govern attention and working memory, which interact with timekeeping processes

10. FUNCTIONAL SIGNIFICANCE OFBRAIN CIRCUITS THAT GOVERNINTERVAL TIMING Pairwise subtractions of brain activation during time discrimination (T), pitch discrimination (P), and the sensorimotor control (C) tasks were conducted for each period.

12. ILLUSIONS OF TIME Emerging neuroimaging research suggests that the mechanisms may be partially context dependent.

13. CONCLUSIONS

14. THANK YOU!