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1. SURGERY SEMINAR PRESENTED BY, 
ASWATHY  K  SASI
  www.similima.com 1 
2. hydronephrosis www.similima.com 2 
3. definition An aseptic dilatation of the kidney due to a partial or complete obstruction to the outflow of urine
Two types www.similima.com 3 
4. www.similima.com 4 
5. Unilateral hydronephrosis By some form of ureteric obstruction, with the ureter above the obstruction being dilated 
Causes
    1) Intraluminal
    2) Intramural ( in the
        walls) 
    3) Extramural 
        obstruction  www.similima.com 5 
6. INTRALUMINAL
      - stones & papillary necrosis in DM,  analgesic nephropathy 
 
INTRAMURAL
   1) Congenital
        - PUJ dyskinesia/ Achalasia of PUJ
        - due to failure of trasmission of 
          neuromuscular impulses through the narrow
          PUJ
        - male:female= 2:1
        - common in males on left side www.similima.com 6 
7. 2) Ureterocoele
        - congenital narrow ureteric orifice
3) Physioslogical narrowing of the PUJ leading to PUJ obstruction
4) Inflammatory stricture following removal of a calculus, repair of a damaged ureteric segment or tuberculous infection
5) Neoplasm of the ureter or bladder cancer involving ureteric orifice www.similima.com 7 
8. EXTRAMURAL OBSTRUCTION
Tumor from adjacent structures 
       Eg: CA cervix, prostate, rectum, 
             colon, caecum
Idiopathic retroperitoneal fibrosis
Retrocaval ureter
Obstruction by aberrant vessels
Retrocaval ureter
Horse shoe kidney
 www.similima.com 8 
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10. Clinical features
Insidious onset of mild pain or dull aching in the loin
Attacks of renal colic
Intermittent hydronephrosis
    - after an attack of acute renal pain, a swelling in the loin is found. Some hours later, following the passage of a large volume of urine, the pain is relieved & the swelling disappear          “DIETL’S CRISIS”; common in hydronephrosis www.similima.com 10 
11. Bilateral hydronephrosis/    ormond’s disease  Result of urethral obstruction; but may also be caused by one of the lesions described above occuring on both sides
Causes
In children
     - phimosis
     - meatal stenosis
     - posterial urethral valve
     - bilateral vesico ureteric reflex  www.similima.com 11 
12. In young adults
    - stricture urethra- due to gonococcal 
      urethritis
    - bilateral aberrant vessels- a branch of
      renal artery & veins which cross the 
      ureters
Middle ages & above
    - BHP (common cause)
    - Contracture of the bladder neck
    - Idiopathic retroperitoneal fibrosis  
Physislogical 
    - pregnancy due to growing foetus & partly
      due to progesterone  www.similima.com 12 
13. Pathogenesis
In a kidney with an extra renal pelvis
     - the dilatation first affects the pelvis alone( pelvic hydronephrosis) if the obstruction is not relieved the calyces become increasingly dilated & the renal parenchyma is progressively destroyed by atrophy 
In a kidney with an intra renal pelvis
     - destruction of parenchyma occurs more rapidly
If the disease progresses, leads to a non functional kidney
If the disease is bilateral- uraemia  www.similima.com 13 
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15. Clinical features
From lower UT obstruction
    - dull loin ache 
    - symptoms of bladder outflow obstruction 
      predominate
From upper UT obstruction
    - although both systems are obstructed, 
      symptoms may be referred to one side only
From pregnancy 
    - dialatation of ureter & renal pelvis occurs 
      early in pregnancy & becomes more marked 
      until 20 th week
    - results from high levels of circulating 
      progesterone on ureteric smooth muscles 
    - ureters returns to their normal size within 12
      weeks of delivery www.similima.com 15 
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17. investigations Plain X ray KUB
USG
CT scan
Intra venous pyelography
Isotope renography
Retrograde pyelography(RGP)
Blood urea
Creatinine
 www.similima.com 17 
18. treatment Indications for operation :
   1) bouts of renal pain
   2) increasing hydronephrosis
   3) evidence of parenchymal damage
   4) obstruction www.similima.com 18 
19. Principles of surgery
Non inflammatory kidney with thinned out cortex with hydronephrosis 
   (pyonephrosis- nephrectomy)
If the cortical thickness is adequate by US, even though it is non inflammatory kidney, a preliminary nephrostomy to decompress the system has to be done www.similima.com 19 
20. Grades of renal pelvic diameter & management Grade 1       mild           11-20 mm
         - Conservative / non operative
           management
Grade 2       moderate    21-35 mm
         - Conservative management
Grade 3       severe        >35 mm
         - Operated early
         - Anderson-Hyner Pyeloplasty to prevent
           permanent damage to kidney www.similima.com 20 
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