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Transcription: DNA  mRNA

Transcription: DNA  mRNA. Remember…. DNA is the genetic code and is found in the nucleus . The genetic code is used to make proteins , which you are made of. But…proteins are made on the ribosomes. Remember…. nucleus. DNA. So how does the code get from the nucleus to the ribosomes?.

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Transcription: DNA  mRNA

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  1. Transcription:DNA  mRNA

  2. Remember… • DNA is the genetic code and is found in the nucleus. • The genetic code is used to make proteins, which you are made of. • But…proteins are made on the ribosomes.

  3. Remember… nucleus DNA

  4. So how does the code get from the nucleus to the ribosomes? RNA

  5. Structure of RNA • RNA differs from DNA in 3 ways: • RNA is a single strand. • RNA has the sugar ribose. • RNA has the nitrogen base uracil instead of thymine.

  6. Structure of RNA Single strand

  7. 3 Types of RNA • Messenger RNA (mRNA) • Ribosomal RNA (rRNA) • Transfer RNA (tRNA)

  8. mRNA • mRNA delivers the instructions for making a protein from the nucleus to a ribosomein the cytoplasm.

  9. Transcription • DNA cannot leave the nucleus. • However, its code can be copied by mRNA and taken out of the nucleus.

  10. Transcription • First, the enzyme RNA polymerase binds to DNA and separates the DNA strands.

  11. Transcription • Then, a strand of mRNA is transcribed (copied) using one DNA strand as a template.

  12. Transcription • To copy the code, RNA nucleotides are added using the base pairing rules for DNA, except that in RNA, uracil pairs with adenine. • (G – C, A – U)

  13. Practice Transcribing • Let’s practice transcribing a strand of DNA: • DNA: G T C A G A T A C • mRNA:________________ C A G U C U A U G

  14. Transcription Animation • http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/transcription.swf

  15. RNA Processing • The sequences that code for proteins are called exons because they are “expressed” in the synthesis of proteins. • The introns do not code for proteins and are cut out of the mRNA sequence before it leaves the nucleus. • The remaining exons are spliced together.

  16. After Transcription • The single strand of mRNA leaves the nucleus and enters the cytoplasm. • It will then travel to a ribosome where its code will be translated into a protein.

  17. After Transcription

  18. Transcription & Translation Transcription Translation In the nucleus In the cytoplasm (ribosome)

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