DiscovIR-GC ™. The Epidemic is coming (Tucson News KOLD/KMSB). Synthetic Analog Problem. DEA Temporary Placement of JWH-018, JWH-073, JWH-200, CP47,497 and CP47,497 C8 homolog, MDPV, Mephedrone, Methylone on Schedule 1 H.R. 1254: Synthetic Drug Control Act of 2011
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Class 1: Classic Cannabinoid
Class 2: Basic non classic Cannabinoid
Class 3: Naphtoylindole
Class 4: Phenylacetylindole
Class 5: Benzoylindole
JWH-018 1’napthyl isomer
AM2201 2’napthyl isomer
AM694 4-iodo isomer
RCS-4 C4 homolog
RCS-8 3-methoxy isomer
RCS-8 4-methoxy isomer
JWH-200 2’ napthyl isomer
AM-694 3-iodo isomer
RCS-4 3-methoxy isomer
RCS-4 2-methoxy isomer
JWH-073 2’napthyl isomer
Step #1 Separation by Gas Chromatography
Step #2 Controlled Deposition - unique solid phase deposition.
Step #3 Chemical Identification - using FTIR specificity (positional and stereoisomers)
NIST Traceable polystyrene film
for daily calibration test
Acquisition of solid phase transmission spectra through
Infrared beam fixed in position
Start Sample 2 RT= 0.0 min
End Sample 2 RT= 20.0 min
ZnSE Disc rotates
Records linear position
and rotary position for
For every spectra
Sample deposit ZnSe window
Precision Vacuum Backplate
Sample collection mechanism
Resistive Heaters +/-5oC
Disc auto load/unload
4 inch diameter ZnSe disc, washable & reusable Holds 50 hours of chromatography in spiral track Auto location, Checks for sample, Post dep. analysis
no real change of procedure needs to be employed
Comparable To Solid phase/condensed phase IR spectra run with:
- KBR pellet
- Nujol Mull
Noise or Split Band?
RT 21.9 minutes
after 600 scans
Rescan enables increases SNR for Decision
Most clandestine tablets are mixtures
Can obtain an infrared spectra for each component
With the DB-35 column can separate BZP, TFMPP and MDMA (see figures 4-7)
Isomer determination for MDMA, TFMPP and CPP (to name just a few)
Resolve and identify mixed analytes in a single instrument and procedure.
GC-FTIR provides two analytical methods in one operation.
High resolution solid phase spectra
Self-cleaning IR disk. No need to manually clean off old samples.
Automatic operation up to 50 hours: Autosampler-compatible.
Spectral identification library software.
Flow splitting: can interface with existing GC–MS instrumentation.
Real-time or post-run data collection. Allows re-analysis of deposited samples