Introduction. History of the progestin-only pill (POP) Developed in mid 1960sSafety concerns with estrogen Four generations of POPsClassification variedAvailability in the United States - $30/monthnorethindrone 0.35 mgMicronor, NorQD, camilla, errin, nora-BE. Physiologic Effect of POPs. Thickening of cervical mucusMakes sperm penetration challengingTubal motility and cilia are slowedSuppression of LH surge Dose dependent
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