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Mike P. Holzer, MD Annett Mannsfeld, MSc Angela Ehmer, MSc Gerd U. Auffarth, MD

International Vision Correction Research Centre. mike.holzer@med.uni-heidelberg.de www.lasik-hd.de. Corneal changes following INTRACOR femtosecond laser treatment. Mike P. Holzer, MD Annett Mannsfeld, MSc Angela Ehmer, MSc Gerd U. Auffarth, MD. Study and research has

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Mike P. Holzer, MD Annett Mannsfeld, MSc Angela Ehmer, MSc Gerd U. Auffarth, MD

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  1. International Vision Correction Research Centre mike.holzer@med.uni-heidelberg.de www.lasik-hd.de Corneal changes following INTRACOR femtosecond laser treatment Mike P. Holzer, MD Annett Mannsfeld, MSc Angela Ehmer, MSc Gerd U. Auffarth, MD Study and research has been supported by Technolas Perfect Vision GmbH, Heidelberg, Germany Dept. of Ophthalmology, University of Heidelberg, Germany Acting chairman: G.U. Auffarth, MD

  2. Femtosecond Laser: Femtec Femtec (Technolas Perfect Vision GmbH, Heidelberg, Germany) • CE mark • FDA 510k clearance • 40 kHz • FEMTEC fixation of eye: • Curved patient interface • less stress on cornea • less suction pressure Mike P. Holzer, MD

  3. INTRACOR • Purely intrastromal refractive treatment with Femtec Laser • No cut of epithelium, Bowman‘s or Descemet • No incision, pockets etc. • Cut design and stromal depth algorithm depending on refractive error • Duration approx. 20 seconds Mike P. Holzer, MD

  4. Patients & Methods • Ongoing prospective, multicenter study • Approval of Ethics Committee (Univ. of Heidelberg) • Intrastromal correction of presbyopia • 25 patients treated between July & Sept. 2008 • Age 56.2 ± 5.79 years (range 47 – 67 years) • Up to 6 months postoperative follow up • Minimum near add +2.0 D • Non dominant eye treated Mike P. Holzer, MD

  5. INTRACOR Presbyopia Cavitation gas in ring cuts Gas escaped from cornea 1 hour postop 1 day postop 4 days preop 4 days preop 1 week postop 1 hour postop Mike P. Holzer, MD

  6. Development near UCVA n=25 n=24 n=25 n=25 n=25 * * p < 0.01 Friedman-Test 0.7 = 20/100 0.26 = 20/30 DCNVA:0.23 ± 0.08 logMAR Mike P. Holzer, MD

  7. Development near UCVA preop 3M postop Mike P. Holzer, MD

  8. Near and distance visual acuity Distance correction preop 3M postop Sphere +0.75 D ± 0.23 D +0.15 ± 0.31 D Cylinder -0.33 D ± 0.17 D -0.42 ± 0.23 D Mike P. Holzer, MD

  9. Pentacam pre- / 3M postop: Exp. 1 Preop 3M postop central steepening Mike P. Holzer, MD

  10. Pentacam pre- / 3M postop: Exp. 2 Preop 3M postop central steepening Mike P. Holzer, MD

  11. Corneal asphericity Q-value (6.0 mm)  Q-value more negative following INTRACOR treatment Mike P. Holzer, MD

  12. Summary: INTRACOR • High potential forcorrectionof presbyopia • Non invasive  verylowriskforinfections • Stablerefractiveoutcomeduringfollowupperiod • Significantgain in uncorrectednearvisualacuity • Slightcentralsteepeningand negative q-value • Noweakeningofcornea • Future treatments: lowmyopia / hyperopia / astigmatism, retreatmentsofremainingrefractiveerrorsfollowingIOL- or Excimer Laser Surgery Mike P. Holzer, MD

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