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Echemi Chemical 3-Bromo-L-phenylalanine Description

White to off-white powder<br>

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Echemi Chemical 3-Bromo-L-phenylalanine Description

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  1. CAS No:82311-69-1 Formula:C9H10BrNO2 Synonyms:3-Br-L-Phe-OH;3-Bromo-L-phenylalanine;(L)-Bromophenyl alanine;(S)-2-Amino-3-(3'-Bromophenyl)Propanoic Acid China Export:From 2018.11 to 2019.11, total export volume of 3-Bromo-L-phenylalanine from China was 104,569,403KG while total export value was $249,619,259. The biggest proportion of exporting volume in the last 12 months was 10.70% in 2019.07. Echemi Chemical 3-Bromo-L-phenylalanine Description White to off-white powder Echemi Chemical 3-Bromo-L-phenylalanine Basic Attributes CAS No：82311-69-1 Molecular Formula ：C9H10BrNO2 Molecular Mass ：244.0852 Exact Mass ：242.989487 PSA ：63.3 LogP ：-0.8 InChIKeys ：GDMOHOYNMWWBAU-QMMMGPOBSA-N H-bond Acceptor ：3 H-bond Donor ：2 SP3 ：0.22 RBN ：3 Echemi Chemical 3-Bromo-L-phenylalanine Characteristics Density ：1.6±0.1 g/cm3 Bolling Point ：368.4°C at 760 mmHg Flash Point ：176.6±25.1 °C Refractive Index ：1.609 Solubility ：Slightly soluble in water.

  2. Echemi Chemical 3-Bromo-L-phenylalanine Safety Information HS Code ：2922499990 P Code ： P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 Hazard Statements ：H315 Echemi Chemical 3-Bromo-L-phenylalanine Production Methods (2S)-3-(3-Bromophenyl)-2-(ter^butoxycarbonylamino)propionic acid (5.0 g, 14.5 mmol) was suspended in 4M HCl in 1 , 4-dioxane (75 mL) and stirred for 16 h at r.t. The white precipitate was filtered and washed with -Bromo-L-phenylalanine(2jS)-3-(3-Bromophenyl)-2-(tert-butoxycarbonylamino)propiomc acid (5.0 g, 14.5 mmol) was suspended in 4M HCl in 1, 4-dioxane (75 mL) and stirred for 16 h at r.t.. The white precipitate was filtered and washed with EtTo a stirred solution of compound 10-01-1 (5 g, 0.0141 mol) in 65% aq. ethanol (50 mL) was added Et3N (10 mL, 0.0707 mol), compound 10-01-2 (3.45 g, 0.0141 mol) slowly at RT. The resulting mixture was stirred at 75C for 16 h. The reaction was monitored by LCMS. The reaction mixture was neutralized with 1.5 N HC1, precipitated solid was filtered, washed with water and dried to get the product 10-01-3 as an off white solid. (5.5g, 80.6 %) EtINTERMEDIATE 65 3

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