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Jyrki Törnvall, Mesimäki, Risto Kontio

Jaw bone defect – Soft tissue defect. Jyrki Törnvall, Mesimäki, Risto Kontio. Preop. May 07. ASCs , ß TCP , BMP 2. From FAT to bone in few months. In the OR. In the Lab. 1) 1dl fat containing 100 000 stem cells. 2) Fat is broken to 1-cell suspension

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Jyrki Törnvall, Mesimäki, Risto Kontio

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  1. Jawbonedefect – Soft tissuedefect Jyrki Törnvall, Mesimäki, Risto Kontio

  2. Preop

  3. May 07 ASCs,ßTCP,BMP 2

  4. FromFAT to bone in fewmonths In the OR In the Lab 1) 1dlfatcontaining 100 000 stemcells 2) Fat is broken to 1-cell suspension and stemcellsextracted 7) The TRAM-flapcombination is raisedand transplanted to the defectsite. Itis rigidlyfixed with titaniumscrews. 3) Stemcells and expanded to abt 1 million 4) Cellsarecombinedwithbiomaterial and GF is added 6) The constructis placed in a preparedmusclepouch 5) The combination is placed in a titaniumcage SuomenKuvalehti

  5. October 07

  6. October 07

  7. December 07

  8. March 08

  9. October 08

  10. 2) Isolate and culture adipose stem cells (10 days ) 3) Combine cells with growth factor BMP-2 and biomaterial 1) Harvest adipose tissue * * * * * * * 4) The mix is placed directly into the patients defect site * = growthfactor = biomaterial Ameloblastoma treatment usingadiposestemcellsand biomaterials =adiposetissue

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