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Lab-Scale Extruder & Spheronizer Combo_ Revolutionizing Granulation Technology

Lab-Scale Extruder and Spheronizer Combo is a seamlessly integrated system poised to redefine granulation in formulation research and product development. The Extruder component, featuring four interchangeable heads, facilitates versatile low-pressure granulation techniques on a bench-top scale, accommodating batches as small as 200 grams. Its adaptability and indicative results make it a cost-effective and efficient solution for evaluating diverse formulations.<br><br>

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Lab-Scale Extruder & Spheronizer Combo_ Revolutionizing Granulation Technology

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  1. Lab-Scale Extruder & Spheronizer Combo: Revolutionizing Granulation Technology Introduction The Lab-Scale Extruder and Spheronizer Combo is an innovative and seamlessly integrated system designed to transform granulation processes in formulation research and product development. By combining advanced extrusion and spheronization capabilities, this system enables precise control over particle size and shape, making it an essential tool for industries such as pharmaceuticals, chemicals, and food processing. With its robust design and state-of-the-art features, the VJ Instruments Extruder and Spheronizer Combo sets a new benchmark in granulation technology. The Role of Granulation in Formulation Research Granulation is a crucial process in pharmaceutical, chemical, and food industries, as it affects the flowability, compressibility, and bioavailability of powders. It involves particle size enlargement by agglomerating smaller particles into granules or spheres. This process enhances uniformity, stability, and ease of handling, making granulation an integral step in formulation development. There are two main types of granulation: 1. Wet Granulation: Uses liquid binders to agglomerate powders, commonly used in pharmaceutical and food industries. 2. Dry Granulation: Achieved through compression and mechanical forces, ideal for moisture-sensitive materials. The Lab-Scale Extruder and Spheronizer Combo offers a comprehensive solution for granulation, combining extrusion and spheronization into a single platform for efficient and scalable research applications. Extruder Component: Precision in Low-Pressure Granulation Key Features of the Extruder: ● Four interchangeable extrusion heads for enhanced versatility. ● Bench-top design to accommodate laboratory-scale batches as small as 200 grams.

  2. ● Low-pressure granulation techniques to maintain product integrity. ● Cost-effective approach for evaluating diverse formulations. ● Consistent and reproducible results for better formulation decision-making. How the Extruder Works The extrusion process involves forcing a wet or dry formulation through a perforated screen to create uniform extrudates. These extrudates then undergo spheronization to form spherical granules, which enhance flowability and compressibility in downstream processing. The extruder’s four interchangeable heads offer flexibility in shaping the extrudates, allowing researchers to explore different granule sizes and structures before moving to full-scale production. Spheronizer Component: Advanced Control Over Particle Shape Key Features of the Spheronizer: ● 230 mm diameter friction plate for efficient spheronization. ● Adjustable plate speeds to control the size and density of spheres. ● Particle size range from 0.5 mm to 10.0 mm for diverse applications. ● Easy disassembly for quick cleaning and maintenance. ● GMP-compliant design ensuring adherence to industry standards. ● Stainless steel control panel for precision control and ease of operation. How the Spheronizer Works Once the extrudates are produced, they are transferred to the spheronizer, where they undergo rapid movement on a friction plate. This action rounds the extrudates into uniform spheres, enhancing uniformity, compressibility, and dissolution rates in final product formulations. The adjustable plate speed allows researchers to fine-tune the spheronization process for optimal results. Applications of the Lab-Scale Extruder & Spheronizer Combo 1. Pharmaceutical Industry In pharmaceuticals, granulation technology is essential for producing oral solid dosage forms such as tablets and capsules. The Lab-Scale Extruder and Spheronizer Combo aids in: ● Controlled release formulations by producing uniform spherical granules.

  3. ● Improved drug stability and bioavailability. ● Enhanced powder flow properties for seamless tablet compression. ● Optimizing excipient compatibility for better drug formulation outcomes. 2. Chemical Industry For the chemical industry, granulation enhances material handling, dispersion, and reactivity. The Extruder & Spheronizer Combo assists in: ● Catalyst preparation by producing uniform granules for chemical reactions. ● Pigment and dye granulation for consistent color distribution. ● Fertilizer production by creating free-flowing spherical granules. 3. Food Industry In food technology, granulation improves product texture, stability, and solubility. The Extruder & Spheronizer Combo supports: ● Encapsulation of flavors and active ingredients. ● Granulation of dairy and protein powders. ● Production of instant beverage granules for better solubility. Benefits of the VJ Instruments Extruder & Spheronizer Combo 1. Integrated System for Seamless Workflow The combination of extrusion and spheronization in one system streamlines the granulation process, reducing processing time and improving efficiency. 2. Cost-Effective Formulation Testing With small batch capabilities, researchers can optimize formulations without the high costs associated with full-scale production. 3. GMP-Compliant and Industry-Ready Designed to meet stringent Good Manufacturing Practices (GMP), ensuring high-quality standards for pharmaceutical, chemical, and food formulations. 4. Flexible and Scalable From bench-top research to commercial production, the system provides a scalable solution for various granulation needs. 5. User-Friendly Design

  4. With easy disassembly, stainless steel control panels, and adjustable settings, this system offers a hassle-free user experience. Conclusion The Lab-Scale Extruder & Spheronizer Combo from VJ Instruments represents a significant leap forward in granulation technology. By seamlessly integrating extrusion and spheronization, this system enables precise Secondary Sales Information Management for improved formulation research and product development. With its versatile, GMP-compliant, and cost-effective design, it is the ultimate solution for industries requiring reliable secondary sales data for granulation processes. Whether in pharmaceuticals, chemicals, or the food industry, this innovative system empowers researchers to achieve greater control, efficiency, and quality in their formulations. As granulation technology continues to evolve, the VJ Instruments Extruder & Spheronizer Combo stands as a powerful and indispensable tool, redefining industry standards and unlocking new possibilities for innovation.

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