Cough Guidelines The European Perspective. Alyn Morice University of Hull. Points of difference. The majority of the guidelines from both ERS, BTS and ACCP are consistent and agreed. However there are some areas of disagreement. Evidenced based vs opinion based.
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The European Perspective
University of Hull
The majority of the guidelines from both ERS, BTS and ACCP are consistent and agreed. However there are some areas of disagreement.
Compared with preceding meta analysis
12 trials, 19 meta-analyses, 40 endpoints
Only 67% agreement
Meta analysis did not predict the result of the RCT in 35% of casesDiscrepancies between meta-analyses and subsequent large randomized, controlled trials LeLorier J NEJM 1997 337 536-542
The chief merit of language is clearness, and we know that nothing detracts from this so much as unfamiliar terms
Ford AC, Forman D, Moayyedi P, Morice AH.
Cough in the community: a cross sectional survey
and the relationship to gastrointestinal symptoms.
Mittal NEJM 1997
REFLUX COUGH QUESTIONNAIRE
Everett Resp Med 2006
Posterior commisure hypertrophy
Vocal fold oedema
individual as recorded by HACC
the VR1 cough receptor
76 patients with intractable cough
Cystic fibrosis 8%
Morice AH et al 2006 AJRCCM