Avian Influenza – What does it all mean?. Important Background Information Island Paravets and Residents. Avian Influenza: Background. Waterbirds are the natural reservoir of all Influenza “A” viruses. Wild birds and these diseases have evolved together naturally over time
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Important Background Information Island Paravets and Residents
Influenza strains are named for their specific types of protein spikes that act as a “lock and key” mechanism with host cells
H = hemagglutinin (16 types)
N = neuraminidase (9 types)
is one of the 144 possible combinations. One subtype (HPAI H5N1) is of concern worldwide.
Source: Horimoto and Kawaoka, 2005.
Significant Variation within current HPAI H5N1 subtypes
Sturm-Ramirez et al. 2005
Why are we so worried about “bird flu”?
HPAI H5N1 Human cases
Dec. 2003 to May 2006
Indonesia 32 24 207 million
Thailand 22 14 65 million
Vietnam 9342 84 million
147 80 356 million
Average = 1 case per 2.4 million people
Average = 1 death per 4.5 million people
Compared to 230 human cases of HPAI H5N1 worldwide in nearly a decade…..
Each year in the U.S. 5-20% of the population will get HUMAN seasonal flu
How could HPAI H5N1 reach islands ?
Commercial /Illegal Trade of Birds, Poultry Meat, Eggs
Compensation for flocks is essential for accurate reporting
Sale or slaughter of sick birds is known to spread HPAI in AsiaAvian Influenza:What You Should Know