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How to Conduct a Targeted Literature Search for Clinical Manuscripts: A Guide for Physicians Group: pubrica.com Email: sales@pubrica.com
Introduction • Targeted literature searches are key to writing high-quality clinical manuscripts. • They contribute meaningfully to evidence-based practice. • Frameworks like PICO and PRISMA help guide this process. sales@pubrica.com +44 161 394 0786 +91 9884350006 pubrica.com • Copyright © 2025 pubrica
Why a Targeted Search Matters in Clinical Research • Decreases information overload by excluding irrelevant studies. • Supports evidence synthesis for hypothesis development. • Enhances methodological rigor and increases publication potential. sales@pubrica.com +44 161 394 0786 +91 9884350006 pubrica.com • Copyright © 2025 pubrica
Define the Clinical Research Question • Use the PICO framework: Population, Intervention, Comparator, Outcome. • Example: Adults with type 2 diabetes, metformin vs. lifestyle changes. • Clear research questions drive focused literature retrieval. sales@pubrica.com +44 161 394 0786 +91 9884350006 pubrica.com • Copyright © 2025 pubrica
Use Structured Search Strategies • Identify keywords, synonyms, and use MeSH terms. • Use Boolean operators: AND, OR, NOT to refine results. • Apply filters: article type, date, language, age group. sales@pubrica.com +44 161 394 0786 +91 9884350006 pubrica.com • Copyright © 2025 pubrica
Document and Export the Search Strategy • Maintain a search log for transparency and replicability. • Record database, keywords used, filters applied, results found. • Example: "PubMed – statins AND diabetes AND MI – RCT – 103 results." sales@pubrica.com +44 161 394 0786 +91 9884350006 pubrica.com • Copyright © 2025 pubrica
Use Advanced Tools and Citation Managers • PubMed Clinical Queries sorts by study type. • Tools like EndNote, Zotero, Mendeley manage citations. • Organize sources by theme or manuscript sections. sales@pubrica.com +44 161 394 0786 +91 9884350006 pubrica.com • Copyright © 2025 pubrica
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