. 38 y.o. male has been on and off ARVs for 2 yrs, secondary to substance abuseNew lesions on legsCD4 80, VL 80,000Restart Antiretrovirals (ARVs)Special clinical features: edema lower legs/ groin regionwoody feeling to upper legs. . If lymphedema, ARVs may not be enoughFor those who need chemotherapy, liposomal doxorubicin is first line chemotherapy in this country.