Immunoglobulins as Binding Proteins. Lecture 10, Medical Biochemistry. Lecture 10, Outline. Structures of Immunoglobulins Functional and Structural Differences between class members The immunoglobulin fold motif in immunoblobulins and other binding proteins. Immunoglobulin Function.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Lecture 10, Medical Biochemistry
has two binding sites
of two types of
polypeptides, H chains
for "heavy" molecular
weight and L chains for
“light” molecular weight.
IgG molecules treated for a limited time
with the protease papain can be cleaved
into 2 kinds of fragments. Under these
conditions, papain only hydrolyzes the H
chain at a single peptide bond located in
the "hinge" region between two
immunoglobulin fold domains.