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1. Cognitive Psych Neural Basis of Cognition – a crash course
3. The Soma The cell body of the cell
Contains the “engine” of the cell
Organelles
Nucleus
Contains the DNA
Mitochondrion
Energy production
Ribosomes
Endoplasmic reticulum
4. Cell membrane The outer structure of the cell
Two layers of fat molecules
Selectively permeable – some substances can pass at will, some not at all, some can come in sometimes, but not other times.
Ion channels – protein gates that allow ions to pass through
Generally closed
6. Dendrites Branch-like projections around the soma
Receive information from other cells
7. Axons Long tubular looking structure
Carries information away from the cell and towards another cell
Myelin sheath – axon is covered by an electrically insulating phospholipid layer
Functions to speed up neural transmission
Protects the axon
Node of Ranvier – gaps in the myelin sheath
9. Axon terminal and synapse At the end of the axon is a bulge
Presynaptic terminal
Axon terminal
Terminal button
“transmits” information to another neuron
Synapse – space between the axon of one neuron and the dendrite of another neuron
Synaptic cleft
11. Neural communication Neurons communicate in two ways
Electrical signal: within a neuron
Chemical signal: between neurons
Electrical signal is sent from one part of the neuron to the other: The signal travels from the dendrite through the cell body to the axon
Dendrites receive the signal from another neuron
Axons send the signal to other neurons
Chemical signal is sent from the axon of one neuron to the dendrite of another neuron
12. Electrical Communication Resting potential: all neurons rest at -70 mV.
Positive ions are outside the cell
Forces trying to get them inside
Shocks makes ion channels open
Positive ions come in (Na+)
Charge changes – action potential
Potential is propagated down the axon
13. Propagation of the action potential.
15. The synapse
16. Action potential results in NT released into the synapse
NT contacts dendrite of another cell
Dendrite contains receptors
NT binds to receptors
Initiates changes that can eventually stimulate an action potential in the postsynaptic neuron.
17. Parts of the Brain 3 major divisions
Hindbrain: Cerebellum; Pons; Medulla
Forebrain: Cortex, amygdala, hippocampus, thalamus, hypothalamus
Midbrain
19. Hindbrain Cerebellum: Extremely large area, millions of neurons
Responsible for coordination of movement
timing
Eyeblink conditioning
20. Pons
Important for sleep and especially dreaming
Part of the “brainstem”
Phylogenetically old
21. Medulla
Controls all vital functions of the body including breathing and heart rate
Forebrain
Thalamus
Primary relay station of the brain
Almost all sensory information passes through before going elsewhere
Amygdala
Responsible for many aspects of emotion
Emotional learning
22. Hypothalamus
Regulates autonomic nervous system
Regulates hormones, “4 F’s”; Feeding, Fighting, Fleeing, and sexual behavior
Controls the pituitary gland
Basal ganglia
motor control, cognition, emotions and learning
Nucleus Accumbens – receives dopaminergic input from the VTA
Reward center
Olds and Milner
Important aspects of attention and thinking
23. Hippocampus
Especially important for learning and memory
Resolving conflict
Cerebral Cortex
Does just about everything
Many think that the cortex is what makes humans the way they are
Cortex is broken up into 4 lobes:
Frontal lobe: the front of the brain
Temporal lobe: side, the temples
Parietal lobe: kinda middle portion
Occipital Lobe: very back
25. Frontal lobe – very large, many functions
Precentral gyrus: Primary motor cortex
Generation of movement
Broca’s area – production of speech
Prefrontal cortex
Integration of many types of information
Thinking, planning, decision making
Temporal lobe
Audition
Wernicke’s area: Language comprehension
26. Parietal lobe
Somatosensory function (touch, vibration, pain)
Sensory areas have specific parts dedicated to certain parts of the body
homunculus
Association areas
Combination of all senses with vision
Occipital lobe
Vision: Primary visual cortex
Many aspects of vision
28. Occipital lobe
Vision: Primary visual cortex
Temporal lobe
Audition
Wernicke’s area: Language comprehension
29. Studying the human brain Study cases of brain damage
Example: Phineas Gage
Neural imaging – technology that allows inspection of an intact brain
EEG: electroencephalogram – electrodes are placed on the scalp.
It records the electrical activity of neurons.
Event-related potentials
Problem: It records from thousands of neurons at a time; not very precise
31. “CAT” scan: Computerized tomography
Computer enhanced 3-D X-Rays
Not much resolution, still life
32. MRI: Magnetic resonance imaging – uses magnetic fields to get brain scans
Just get a picture
34. PET scan: Positron Emission Tomography
– patients are injected with radioactive glucose. The scanner tracks where the glucose moves to. This is used as an indicator of neural activity.
- resolution is fairly low.
36. Functional MRI (fMRI) – Registers changes in the metabolism of cells
Increase in blood flow to the local vasculature that accompanies neural activity in the brain.
Get 3-D picture of real time brain activity
Very expensive
Restricted
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