Lorcaserin: benefits, dosage, side effects-lorcaserin powder manufacturer
www.ok-biotech.com amy@ok-biotech.com
obesity is a serious threat, imposing a vast economic burden on the healthcare
system.
Obesity is the second most common preventable cause of death, second only to
tobacco use.6 Evidence suggests that weight reduction substantially lowers the risk
of related comorbidities and fosters their therapeutic management.7 ,8 Although
bariatric surgery has emerged as the most clinically effective strategy for decreasing
body weight for people with morbid obesity (body mass index (BMI) ≥40) or for
those who cannot be managed otherwise,9 it is a very invasive procedure with
significant risks.10 ,11 At this juncture, behavioural therapy, lifestyle modification
and pharmacotherapy remain the mainstays of treatment. The most appealing
solution for the public in general would be a "weight loss drug". There are many
kinds of weight loss drug, such as sibutramine,orlistat,cetilistat...etc. Lorcaserin is
one of the popular use weight loss drug.
Lorcaserin is a selective 5-HT2C receptor agonist that is thought to decrease food
intake through the central POMC system. Lorcaserin benefits:
-Lorcaserin is used together with diet and exercise to treat obesity.
-Lorcaserin is sometimes used to treat obesity that may be related to diabetes, high
cholesterol, or high blood pressure.
-Lorcaserin will not treat any underlying health condition (such as heart disease,
diabetes, high blood pressure).
3. Lorcaserin dosage
Initial studies demonstrate that lorcaserin is safe when taken at the recommended
lorcaserin dosage of 10 mg twice daily. Because serotonin agonists such as lorcaserin
can cause serotonin syndrome, the manufacturer recommends that patients taking
other serotonergic drugs such as antidepressants avoid coadministration of
lorcaserin. Valvulopathy, a risk with previous weight-loss drugs, has not been
demonstrated with lorcaserin; however, the medication has not been evaluated in
patients with significant valvulopathy or congestive heart failure. Its long-term
effects are unclear because it has not been studied for a period longer than two
years.
Psychiatric symptoms including euphoria, hallucination, and dissociation rarely occur
with recommended dosages, but these have occurred in 19% of patients taking
lorcaserin dosage 40 to 60 mg daily.1 Physical dependence has not been observed
with lorcaserin, although psychic dependence is possible with higher dosages used to