JOURNAL CLUB. CRITICAL APPRAISAL OF DIAGNOSTIC ARTICLE. ALI A. ALBALUSHI EMERGENCY MEDICINE R- 4. Does End Tidal CO2 Monitoring During Emergency Department Procedural Sedation and Analgesia With Propofol Decrease the Incidence of Hypoxic Events?. Randomized, Controlled Trial.
Does End Tidal CO2 Monitoring During Emergency DepartmentProcedural Sedation and Analgesia With Propofol Decrease theIncidence of Hypoxic Events?
Randomized, Controlled Trial
Annals of Emergency Medicine
Article in Press, 2009
* severe chronic obstructive pulmonary disease;
* chronic oxygen requirements;
* hemodynamic instability;
* respiratory distress;
*Inability to provide informed consent;
* allergy to propofol, morphine, or fentanyl (or other components of its formulation);
* or if, in judgment of the attending emergency physician, procedural sedation could compromise patient safety. Informed consent was obtained from each subject.
majority of patients who developed respiratory depression had an ETCO2 change greater than 10% from baseline
loss of waveform was most likely to lead to hypoxia.
Are LR for the test results presented or data neccessery for their calculation provided ?
(TP among diseased)
= 17 / 17 = 1 = 100%
(TN among non diseased)
= 29 / 51 = 0.57 = 57%
= 17 / 39 = 0.44 = 44%
= 29 / 29 = 1 = 100%
= 100 / 43 = 2.3
= 17 / 68 = 25 %
for (+) = 0.33 X 2.3 = 0.79
for (-) = 0.0.33 X 0 = 0