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Predicting visual performance from wavefront quality metrics in cataract. Konrad Pesudovs Katja Ullrich NH&MRC Centre for Clinical Eye Research, Flinders Medical Centre & Flinders University, Adelaide, South Australia. Financial disclosure: The authors have no financial interest.
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NH&MRC Centre for Clinical Eye Research, Flinders Medical Centre & Flinders University, Adelaide, South Australia
Financial disclosure: The authors have no financial interest
PURPOSE: To determine which wavefront quality metrics are most predictive of visual performance in patients with cataract
Inclusions – all types of cataract
Exclusions – ocular comorbidity, unable to measure whole eye wavefront
206 eyes, age 73 years, 58% female
The clinical assessment was conducted by one clinician-KP
Refraction and best corrected
High contrast visual acuity(VA)
Pelli-Robson contrast sensitivity (PRCS)
Pelli-Robson contrast sensitivity under glare (PRCSglare)Population and Visual Performance
Wavefront data exported to VOLPro software v7.25 (Sarver and Associates) and 10th order Zernike expansion derived
Zernike data exported to GetMetrics v.2.02.006 (University of Houston, College of Optometry) by Thibos and Applegate for calculation of wavefront quality metrics
31 metrics of wavefront quality designed to be predictive of visual performance were calculated for the pupil plane and the image plane as per: Thibos LN, Hong X, Bradley A, Applegate RA. Accuracy and precision of objective refraction from wavefront aberrations. J Vis 2004;4(4):329-51.
Linear Regression with SPSS Software V15.0 (SPSS Inc)Wavefront quality metrics
The strongest correlate of all three measures of visual performance was the pupil fraction metric PFWcResults - visual acuity and wavefront quality metrics
Pelli-Robson contrast sensitivity glare & logPFWc, r2=0.32, p<0.001
The strongest correlate of each measure of contrast sensitivity was the pupil fraction metric PFWcResults – contrast sensitivity and wavefront quality metrics
The critical pupil method uses an “area of good pupil” which is a concentric zone
The red circle indicate the largest concentric zone for which the wavefront has reasonably good quality
PFWc which is a critical pupil defined as the concentric area for which RMSw<criterion (λ/4)Pupil fraction metrics