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Fosaprepitant- An intravenous (I.V.) antiemetic drug

Equal in efficacy with oral antiemetics<br>Effective when patient is unable to swallow or digest tablets orally because of emesis<br>Effective in Chemotherapy‐induced nausea and vomiting<br>

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Fosaprepitant- An intravenous (I.V.) antiemetic drug

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  1. Fosaprepitant-An intravenous (I.V.) antiemetic drug By Pharmaffiliates

  2. Intravenous (I.V.) antiemetic drugs - Advantages • Equal in efficacy with oral antiemetics • Effective when patient is unable to swallow or digest tablets orally because of emesis • Effective in Chemotherapy‐induced nausea and vomiting

  3. Fosaprepitant-An overview • An I.V antiemetic medication • Generally exists as its dimegluminesalt • Prevents acute and delayed nausea and vomiting • Chemically, a water soluble, phosphorylated analog of Aprepitant • Converted to Aprepitant after intravenous administration • Aprepitant is a selective high‐affinity antagonist of human substance P/neurokinin 1 (NK1) receptors

  4. Fosaprepitant-At Pharmaffiliates • Reference standards of Fosaprepitant, Fosaprepitant Dimeglumine, Aprepitant available • Reference standards of related impurities of Fosaprepitant are also offered • Stable isotopes Fosaprepitant –D4 Dimeglumineand Fosaprepitant -13C, 15N3 Dimeglumine are also offered • Customized pack sizes available

  5. About Pharmaffiliates • An integrated CRO • Provide service like Custom synthesis, Analytical services, Regulatory services, trainings, NDDS and FTE based projects • Present globally with customers in more than 45 countries • Leading manufacturer and supplier of reference standards of impurities, metabolites, intermediate, glucuronides and stable isotopes • Also specializes in phytochemicals, petrochemicals, Environmental standards, Food and Beverages, Agroproducts

  6. About Pharmaffiliates • Each standard is scientifically purified and characterized • Detailed Certificate of Analysis with chromatograms is provided • COA fulfills all the regulatory requirements • Pharmaffiliates is accreditated with ISO 2009, ISO 17025, ISO Guide 34 and USFDA

  7. Thank you

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