Determinants of Cardiac Output and Principles of Oxygen Delivery Preloader

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Principle of Continuity: Conservation of mass in a closed hydraulic systemBlood is an incompressible fluidVascular system is a closed hydraulic loopVol ejected from left heart = vol received in R heart. Preload. Preload: load imposed on a muscle before the onset of contractionMuscle stretches to new lengthStretch in cardiac muscle determined by end diastolic volume.

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