Antibodies as Drugs. Lauren Lahey April 26, 2007. Overview. An emerging theme Historical breakthroughs Terms to know A look at antibody structure Production of monoclonal antibodies Antibodies as biopharmaceutical Autoimmune Disease Rheumatoid Arthritis Variations and future directions.
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April 26, 2007
Benefit: More readily penetrate tissue
Coupling of antibody fragments to form dimers and tetramers
Increases avidity and cross-linking
Two different antigen specificities
One against the target
The other against effectors
Can cross-link effector cellsInteresting Variations