hormones released from the anterior pituitary or adenohypophysis l.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Hormones Released from the Anterior Pituitary or Adenohypophysis PowerPoint Presentation
Download Presentation
Hormones Released from the Anterior Pituitary or Adenohypophysis

Loading in 2 Seconds...

play fullscreen
1 / 22

Hormones Released from the Anterior Pituitary or Adenohypophysis - PowerPoint PPT Presentation


  • 515 Views
  • Uploaded on

Hormones Released from the Anterior Pituitary or Adenohypophysis. Somatotrophs Human Growth Hormone (hGH) Hypothalamic control hGH releasing hormone hGH inhibiting hormone Target Tissues: General body cells, particularly bone, muscle, cartilage, and the liver.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Hormones Released from the Anterior Pituitary or Adenohypophysis' - Faraday


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
hormones released from the anterior pituitary or adenohypophysis
Hormones Released from the Anterior Pituitary or Adenohypophysis
  • Somatotrophs

Human Growth Hormone (hGH)

Hypothalamic control

hGH releasing hormone

hGH inhibiting hormone

Target Tissues:

General body cells, particularly bone, muscle, cartilage, and the liver.

hormones released from the anterior pituitary or adenohypophysis2
Hormones Released from the Anterior Pituitary or Adenohypophysis
  • Hormone affects:
  • promotes the synthesis of insulin-like growth factors
  • Controls normal growth patterns by increasing protein synthesis, lipolysis, ATP production, and carbohydrate metabolism
  • In adults, it help maintain muscle and bone mass and promote healing and tissue repair
hormones released from the anterior pituitary or adenohypophysis3
Hormones Released from the Anterior Pituitary or Adenohypophysis
  • Hypo-secretion:

During childhood causes Dwarfism

  • Hyper-secretion:

During childhood causes

Gigantism (up to 8 – 9 ft.)

During Adulthood causes

Acromegaly:

Enlargement of the small bones of the hand and feet

Enlargement of the cranium, nose, and lower jaw

Tongue, liver, and kidneys become enlarged

hormones released from the anterior pituitary or adenohypophysis4
Hormones Released from the Anterior Pituitary or Adenohypophysis
  • Thyrotrophs:

Thyroid Stimulating Hormone (TSH)

  • Hypothalamic Control

Thyrotropin Releasing Hormone (TRH)

  • Target Tissue

Follicular cells of the Thyroid gland

  • Hormone affects:

controls the production of T3 and T4

endocrine activity of the thyroid gland
Endocrine activity of the Thyroid Gland
  • Follicular cells:

T3 and T4

  • Target Tissue;

Almost all body tissues

  • Hormone effects:

Increases body metabolism

Increases gluconeogenesis

Increases glycolysis

Increases lipolysis

Increased basal metabolic rate (BMR)

Increases heart rate and force of contraction

endocrine activity of the thyroid gland6
Endocrine activity of the Thyroid Gland
  • Hypothyroidism:

endemic goiter: (due to I2 deficiency)

Myxedema: bagginess under the eyes and swelling of the face.

Arteriosclerosis: due to increase in blood cholesterol

Cretinism: extreme hypothyroidism during infancy and childhood

endocrine activity of the thyroid gland7
Endocrine activity of the Thyroid Gland
  • Hypothyroidism:

Cretinism: Physical and mental growth and development is greatly retarded

  • Hyperthyroidism

Toxic goiter

Graves Disease with exophthalmos

hormones released from the anterior pituitary or adenohypophysis8
Hormones Released from the Anterior Pituitary or Adenohypophysis
  • Corticotrophs

Adrenocorticotropic hormone (ACTH)

  • Hypothalamic Control

Corticotropic releasing hormone (CRH)

  • Target Tissue

Adrenal cortex, Zona Fasciculata

  • Hormone affects:

control production of glucocorticoids such as cortisol

endocrine activity of the adrenal cortex
Endocrine activity of the Adrenal Cortex
  • Zona glomerulosa

Mineralocorticoids such as Aldosterone

  • Hormonal control

renin-angiotensin pathway

permissive effect of ACTH

  • Target tissue:

Principle cells of the DCT and collecting duct

  • Hormone affects:

increases reabsorption of Na+ and water

endocrine activity of the adrenal cortex10
Endocrine activity of the Adrenal Cortex
  • Hyper-secretion:

Aldosteronism:

Hypokalemia, increase in extracellular fluid and blood volume,and hypertension, may also have period of muscular paralysis

  • Hypo-secretion:

Addison’s disease

Mineralocorticoids deficiency, death occurs in four days to two weeks if untreated

endocrine activity of the adrenal cortex11
Endocrine activity of the Adrenal Cortex
  • Zona Fasciculata

Glucocorticoids such as cortisol and cortisone

  • Hormone control:

ACTH

  • Target tissue:

Liver and general body cells

  • Hormone affects:

Stimulates gluconeogenesis by the liver

Decreased glucose utilization by cells

endocrine activity of the adrenal cortex12
Endocrine activity of the Adrenal Cortex
  • Hormone affects:

Elevated blood glucose levels

Reduction of protein stores in all body cells except the liver

increased plasma protein levels

promote lipolysis and beta oxidation of fat

Helps body recover from stress

Prevention of inflammation

endocrine activity of the adrenal cortex13
Endocrine activity of the Adrenal Cortex
  • Hypo-secretion

Addison’s disease - glucocorticoid deficiency

person becomes highly susceptible to disease and deteriorating effects of stress

  • Hyper-secretion:

Cushing’s Syndrome

mobilization of fat from lower body to the thoracic and upper abdominal regions giving raise to “Buffalo Torso”

endocrine activity of the adrenal cortex15
Endocrine activity of the Adrenal Cortex
  • Zona reticularis

Produces small amounts of androgens, mostly dehydroepiandosterone (DHEA), DHEA may be converted into estrogens

  • Hormone Control:

Believed to be ACTH

  • Target tissue:

General body cells

endocrine activity of the adrenal cortex16
Endocrine activity of the Adrenal Cortex
  • Hyper-secretion:

Adrenogenital Syndrome

in females causes beard growth, deeper voice, masculine distribution of body hair, and growth of the clitoris to resemble a penis.

Picture: In pre-pubertal males it causes the rapid develop of secondary sexual conditions

endocrine activity of the adrenal cortex17
Endocrine Activity of the Adrenal Cortex
  • Hyper-secretion:

Adrenogenital Syndrome

in females causes beard growth, deeper voice, masculine distribution of body hair, and growth of the clitoris to resemble a penis.

Picture: Virilizing adrenal hyperplasia in a newborn female baby, DHEA was converted to testosterone

endocrine activity of the adrenal cortex18
Endocrine Activity of the Adrenal Cortex
  • Hyper-secretion:

Picture: micropenis in a newborn baby boy.

micropenis is a result of hypopituitarism and lack of production of LH and therefore testosterone by the cells of Leydig

other thyroid hormones
Other Thyroid Hormones
  • Parafollicular cells

Calcitonin

parathyroid hormones
Parathyroid Hormones
  • Principle Cells

PTH