lecture 25 respiration 2 l.
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Lecture 25 Respiration #2. Diseases detected by PV curves. Air flow transducer - Pneumotachometer. Nitrogen washout. Air flow transducer. Full body plethysmograph. Measurement of airway resistance. Dubois shutter method

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Lecture 25 Respiration #2


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Presentation Transcript
measurement of airway resistance
Measurement of airway resistance
  • Dubois shutter method
  • Measurement of pressure in full body plethysmograph using calibration Pump
  • PV=NRT = gas law
dynamic compliance
Dynamic compliance

C = Volume/Pressure

Volume = integrate flow

Press = difference at flow=0

pressure units
Pressure units
  • Atmospheric pressure ~14.7 pounds/sq inch
  • Daily barometric pressure - 30 cm Hg or 762 mmHg
  • Or 10.3 meters water or 33 ft
pressure calculations
Pressure calculations
  • Today’s barometric pressure = 30.03 cm Hg
  • Or 760 mmHg
  • % Oxygen = 20.94%
  • Partial pressure of oxygen ~160 mmHg
  • Pressure of oxygen in hemoglobin = 100
  • Venous oxygen pressure = 40
hemoglobin dissociation curve
Hemoglobin dissociation curve

Effect pf Ph (Push to Right)

Effect of sickle cell (push to left)

Carbon monoxide

Temperature (push to right)

Organic Phosphates (push to right)

other pressure effects
Other pressure effects
  • High altitude
  • Mount Kilimanjaro
  • Mount Everest
  • Blood Oxygen saturation – ear clip
  • Measurement of PO2
  • Carbon dioxide in brain – hyper ventilation
  • Sleep patterns
  • Artificial lungs
ventilators
Ventilators
  • Design
  • Purpose
  • How it feels
  • High frequency type
  • Neonatal nursery
  • Danger of pure oxygen