GENBO&GENPU - Lesson 1

1. PREDICT GENOTYPES AND PHENOTYPES OF PARENTS AND OFFSPRING USING THE LAWS OF INHERITANCE

2. LEARNING OBJECTIVES: • At the end of the game, the students are expected to; • define the different terminologies related to Mendelian inheritance • determine the possible genotypes of offspring based on the genotypes of the parents using Punnett square • develop students' critical thinking skills by having them interpret questions, solve genetic puzzles, and predict outcomes based on Mendelian principles.

3. PRE - ACTIVITY Each team will select any of the members, and they will create a family tree and share some trait that resembles that of your family member.

4. PRE - ACTIVITY Did you observe many similarities between you and your mother or father? What about your sibling? Seeing similarities with your relative or sibling is much like the concepts discovered by Mendel, but before you learn about these things, you need to familiarise yourself first with the key terms and where you are going to learn these terminologies by playing GENBO.

5. LET’S PLAY GENBO AND GENPU!

6. GENBO • Welcome to the Mendelian Inheritance Genbo Game, an engaging and educational activity designed to help you understand the fundamental principles of genetics discovered by Gregor Mendel. This game will reinforce your knowledge of key terms and concepts related to Mendelian inheritance in a fun and interactive way. The game is inspired by the bingo games Gen for genetics and Bo for bingo. Instead of numbers, terms associated with Mendelian inheritance are on the cards.

7. RULES • Each team will help each other is answering and solving problem. • Every wins they will receive 10 points and the team who will collect a lot of points will be the winner. • Maintain a respectful and fun atmosphere throughout the game.

8. GOAL OF THE GAME • Ensure students are familiar with important terminology related to Mendelian genetics (e.g., genotype, phenotype, alleles, homozygous, heterozygous). • Encourage students to apply their knowledge by solving genetic problems and analyzing inheritance patterns through bingo prompts. • Develop students' critical thinking skills by having them interpret questions, solve genetic puzzles, and predict outcomes based on Mendelian principles.

9. HOW TO PLAY • Distribute Bingo Cards: Give a bingo card, markers, or chips to every student. • Describe the Rules: Using the calling card question or scenario as a guide, students will mark the appropriate spot on their bingo card. • Select and read questions at random from calling cards to use as callouts. • The first student to finish a row, column, or diagonal and yell "genbo!" wins the game. You have the option to play for a complete card blackout.

10. MEET THE PLAYERS • Group 1 • Group 2 • Group 3 • Group 4

11. MEET THE PLAYERS • Group 6 • Group 7 • Group 8 • Group 5

12. EXAMPLE CARDS • G • E • N • B • O • G • E • N • B • O • Homo • zygous • hetero • zygous • Gamete • Segrega • tion • Punnett • Pea • Heredity • Rr • Dominant • Red • Geno • type • Red • Carrier • white • locus • Pink • Gene • F1 • F2 • Rr • Mono • hybrid • Assortment • white • Trait • Free • Free • Pink • Genotype • Mendel • Hybrid • Test cross • Trait • F1 • Carrier • RR • Hybrid • allele • rr • Allele • Mendel • Gene • RR • F2 • white • DNA • Mutation • Recessive • Genetics • dihybrid • Dihybrid

13. EXAMPLE CARDS • G • E • N • B • O • G • E • N • B • O • Homo • zygous • hetero • zygous • Gamete • Segrega • tion • Punnett • Pea • Heredity • Rr • Dominant • Red • Geno • type • Red • Carrier • white • locus • Pink • Gene • F1 • F2 • Rr • Mono • hybrid • Assortment • white • Trait • Free • Free • Pink • Genotype • Mendel • Hybrid • Test cross • Trait • F1 • Carrier • RR • Hybrid • allele • rr • Allele • Mendel • Gene • RR • F2 • white • DNA • Mutation • Recessive • Genetics • dihybrid • Dihybrid

14. BY USING THE LINK BELOW, WE CAN ACCESS THE SETS OF QUESTIONS THAT WE CAN USE IN THE GENBO GAME. • HTTPS://WHEELOFNAMES.COM/JMD-4T7

15. FIVE IN A ROW! • G • e • N • b • O • g • e • N • b • O • g • e • N • b • O • Vertical Line • Horizontal Line • Diagonal Line • RULES • Form any five-in-a-row pattern. It can be diagonal, straight line across, or straight line down. The first player to form a five-in-a-row pattern wins the round.

16. ARE YOU READY TO WIN? • Shout "Genbo" if you get five in a row!

17. The question is under row N. The group will answer the question and look at their cards to see if the correct answer is given, and they will mark it. The process will continue until there is a group to yell GENBO!

18. THIS CARD BELONGS TO • G • E • N • b • O • Punnett • Allele • Rr • Dominant • Red • test cross • Carrier • Gene • F1 • F2 • Mono • hybrid • Trait • Free • Pink • Pea • genome • RR • Hybrid • haploid • Mendel • Sebastian • white • DNA • Mutation • Genetics • Genotype

19. The question is under row O. The group will answer the question and look at their cards to see if the correct answer is given, and they will mark it. The process will continue until there is a group to yell GENBO!

20. THIS CARD BELONGS TO • g • e • N • b • O • Punnett • Allele • Rr • Dominant • Red • test cross • Carrier • Gene • F1 • F2 • Mono • hybrid • Trait • Free • Pink • Pea • genome • RR • Hybrid • haploid • Mendel • Sebastian • white • DNA • Mutation • Genetics • Genotype

21. REMEMBER!! • THOSE GROUPS THAT WIN THE GENBO WILL RECEIVE POINTS, AND EVERYONE WILL PROCEED TO THE ACTIVITY, WHICH IS SOLVING PROBLEMS IN MONOHYBRID AND DIHYBRID CROSSES. • Remember: The goal of each team is to answer correctly to gain points, and the team that collects more will be the winner. • Let’s go!!!

22. LET’S MOVE IN THE LEVEL...

23. GENPU • Players will explore the principles of Mendelian genetics by breeding plants with different traits. The goal is to achieve specific genetic outcomes and solve genetic puzzles using knowledge of dominant and recessive traits, genotypic ratios, and phenotypic expressions.

24. Gregor Johan Mendel is considered the father of genetics, having first introduced both monohybrid and dihybrid crosses. Mendel chose pea plants because their genes do not show the property of linkage. He formulated his two laws, the law of segregation and the law of independent assortment, based on the monohybrid cross and the dihybrid cross, respectively. Monohybrid crosses, mainly, consider one character and form a single hybrid, whereas dihybrid crosses consider two characters. Monohybrid cross refers to the genetic cross that involves the mating of two homozygous individuals consisting of a single character present in a single locus. This type of cross allows us to observe how alleles are transmitted from parents to offspring and how the principles of dominance and segregation operate.

25. PROBLEM 1: A heterozygous purple flower is crossed with a heterozygous purple flower. a. phenotypes / phenotypic ratio b. genotypic ratio c. Percentage

26. Learners must determine the phenotype, or the physical characteristics, of the potential offspring in our mystery box after finishing the Punnett square with the allele at the next station. The box is full of images of possible traits of the offspring.

27. PROBLEM 2: In pea plants, yellow seed is dominant to green seed color. If a heterozygous pea plant is crossed with a plant that is homozygous recessive for seed color, what is the probability that the offspring will have green sseds?

28. A dihybrid cross describes a mating experiment between two organisms that are identically hybrid for two traits. A hybrid organism is one that is heterozygous, which means that it carries two different alleles at a particular genetic position, or locus. Dihybrid cross: The most common example of a dihybrid cross is the cross performed by Mendel by considering two non-linked characters. He crossed yellow coloured round seed with green colored wrinkled seed. This crossing produced hybrid yellow-coloured round seed and gave four phenotypes in the ratio 9:3:3:1 in the second filial generation. Here, “Y” represents the yellow-colored seed and “R” represents the round seed. Therefore, YYRR represents the dominant homozygous condition and represents the yellow-coloured round seed. yyrr represents the recessive homozygous individual, represents the green-coloured wrinkled seed. YyRr represents the heterozygous condition which also represents the yellow coloured round seed.

29. PROBLEM 3 • Set up a punnett square using thefollowing information: • • Dominate allele for tall plants = D • • Recessive allele for dwarf plants = d • • Dominate allele for purple flowers = W • • Recessive allele for white flowers = w • Cross a homozygous dominate parent (DDWW) with a homozygous recessive parent (ddww)

30. a. What is the probability of producing tall plants with purple flowers? Possible genotype(s)? b. What is the probability of producing dwarf plants with white flowers? Possible genotype(s)?

31. c. What is the probability of producing tall plants with white flowers? Possible genotype(s)? d. What is the probability of producing dwarf plants with purple flowers? Possible genotype(s)?

32. HOW CAN UNDERSTANDING THE PRINCIPLES OF INHERITANCE AND GENETIC VARIATION HELP PREDICT THE GENOTYPE AND PHENOTYPE OF OFFSPRING IN LIVING ORGANISMS?

33. OUR WINNERS ARE... • Group ?

34. WORKSHEET • FILE:///C:/USERS/LENOVO/DOWNLOADS/DETECTIVE%20CLUEDON.PDF

35. THANK YOU FOR PLAYING! • See You Next Time!