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Official Full Name Frataxin

Official Full Name Frataxin ;Official Full Name Frataxin ;Official Full Name Frataxin Official Full Name Frataxin

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Official Full Name Frataxin

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  1. fxn fxn Official Full Name Official Full Name frataxin Background Background This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009] Synonyms Synonyms FXN; frataxin; FA; X25; CyaY; FARR; FRDA; frataxin, mitochondrial; Friedreich ataxia protein; Involved Pathway FXN involved in several pathways and played different roles in them. We selected most pathways FXN participated on our site, such as Porphyrin and chlorophyll metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FXN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site. Pathway Name Pathway Name Pathway Related Protein Pathway Related Protein Porphyrin and chlorophyll metabolism EARS2; HMOX1; UGT1A6B; EPRS; UROD; UGT2A2; HEPH; GUSB; BLVRB; HCCSA.1

  2. Protein Function FXN has several biochemical functions, for example, 2 iron, 2 sulfur cluster binding, ferric iron binding, ferrous iron binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FXN itself. We selected most functions FXN had, and list some proteins which have the same functions with FXN. You can find most of the proteins on our site. Function Function Related Protein Related Protein Function Function 2 iron, 2 sulfur cluster binding Related Protein Related Protein CISD1; AOX3; CISD3; AOX3L1; ISCU; CIAPIN1; CMAH; FDX1L; UQCRFS1; FECH Function Function ferric iron binding Related Protein Related Protein MIOX; TH; FTH1B; FTH1A; TF; FTMT; FTHL17; FTL; FTH1; FXN Function Function ferrous iron binding Related Protein Related Protein NT5E; FECH; DNAJC24; TF; FTO; BCO1; PLOD1; FXN; ISCU; ALKBH3 Function Function ferroxidase activity Related Protein Related Protein FXN; FTH1; FTMT; HEPHL1; HEPH; CP Function Function iron chaperone activity Related Protein Related Protein FXN Function Function iron-sulfur cluster binding Related Protein Related Protein REV3L; CMAH; FXN; RTEL1; DPYDA.1; CISD3; NFS1; ELP3; DPYDB; AOX3L1 Function Function protein binding Related Protein Related Protein BNIP3L; RTN4RL1; C2orf62; ARL11; HIST1H3C; KRAS; APPL1; FBXO5; DHX32; KCNQ1 Interacting Protein FXN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FXN here. Most of them are supplied by our site. Hope this information will be useful for your research of FXN. PASK; SDHB; SDHA; ACTN1; PICK1

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